RASINES-PEREA, Zuriñe; KY, Isabelle; CROS, Gérard; CROZIER, Alan

doi:10.3390/diseases6030060

Métadonnées

Afficher la notice complète

Licence d’utilisation du document

RASINES-PEREA, Zuriñe
Unité de Recherche Oenologie [Villenave d'Ornon] [OENO]

KY, Isabelle
Unité de Recherche Oenologie [Villenave d'Ornon] [OENO]

CROS, Gérard

Langue

Article de revue

Ce document a été publié dans

Diseases. 2018, vol. 6, n° 3

Résumé en anglais

Observational studies indicate that the intake of polyphenol-rich foods improves vascular health, thereby significantly reducing the risk of hypertension and cardiovascular disease (CVD). Therefore, the aim of this study was to analyse the remained potential of grape by-products from important Rhône Valley red wine cultivars: Grenache, Syrah, Carignan, Mourvèdre and Alicante. For that, six different extracts from grape pomaces, selected by their antioxidant activity, were studied in vivo during six weeks with spontaneously hypertensive rats (SHR). Extracts used in SHR1, SHR2 and SHR6 groups presented a « rebound effect » on systolic blood pressure, whereas the other extracts do not change it significantly. The bioavailability of Grenache (GRE1) (EA70) seed pomace extract (SHR1 group), Mouvendre (MOU) (EA70) skin pomace extract (SHR5 group) and Alicante (ALI) (EA70) skin pomace extract (SHR6 group) was studied by High Performance Liquid Chromatography with Photodiode Array detector and Electrospray Ionization Mass Spectrometer (HPLC-PDA-ESI-MS) in urine, plasma and tissues to search differences on the metabolism of the different extracts intake.< Réduire

Métadonnées

Partager cette publication !

Licence d’utilisation du document

Grape Pomace: Antioxidant Activity, Potential Effect Against Hypertension and Metabolites Characterization after Intake.

Langue

Ce document a été publié dans

Résumé en anglais

URI

DOI

Unités de recherche