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dc.rights.licenseopenen_US
hal.structure.identifierUnité de Recherche Oenologie [Villenave d'Ornon] [OENO]
dc.contributor.authorRASINES-PEREA, Zuriñe
hal.structure.identifierUnité de Recherche Oenologie [Villenave d'Ornon] [OENO]
dc.contributor.authorKY, Isabelle
dc.contributor.authorCROS, Gérard
dc.contributor.authorCROZIER, Alan
dc.date.accessioned2020
dc.date.available2020
dc.date.issued2018
dc.identifier.issn2079-9721en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/20871
dc.description.abstractEnObservational studies indicate that the intake of polyphenol-rich foods improves vascular health, thereby significantly reducing the risk of hypertension and cardiovascular disease (CVD). Therefore, the aim of this study was to analyse the remained potential of grape by-products from important Rhône Valley red wine cultivars: Grenache, Syrah, Carignan, Mourvèdre and Alicante. For that, six different extracts from grape pomaces, selected by their antioxidant activity, were studied in vivo during six weeks with spontaneously hypertensive rats (SHR). Extracts used in SHR1, SHR2 and SHR6 groups presented a « rebound effect » on systolic blood pressure, whereas the other extracts do not change it significantly. The bioavailability of Grenache (GRE1) (EA70) seed pomace extract (SHR1 group), Mouvendre (MOU) (EA70) skin pomace extract (SHR5 group) and Alicante (ALI) (EA70) skin pomace extract (SHR6 group) was studied by High Performance Liquid Chromatography with Photodiode Array detector and Electrospray Ionization Mass Spectrometer (HPLC-PDA-ESI-MS) in urine, plasma and tissues to search differences on the metabolism of the different extracts intake.
dc.language.isoENen_US
dc.title.enGrape Pomace: Antioxidant Activity, Potential Effect Against Hypertension and Metabolites Characterization after Intake.
dc.title.alternativeDiseasesen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.3390/diseases6030060en_US
dc.subject.halSciences du Vivant [q-bio]/Biologie végétaleen_US
dc.identifier.pubmed29986480en_US
bordeaux.journalDiseasesen_US
bordeaux.volume6en_US
bordeaux.hal.laboratoriesOenologie - EA 4577en_US
bordeaux.issue3en_US
bordeaux.institutionBordeaux INPen_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.identifierhal-03021802
hal.version1
hal.date.transferred2020-11-24T13:54:06Z
hal.exporttrue
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