Input of recombinant phenotyping for the characterization of a novel acyclovir- resistance mutation identified in a patient with recurrent herpetic keratitis
Langue
EN
Article de revue
Ce document a été publié dans
Antiviral Research. 2019, vol. 168, p. 183-186
Résumé en anglais
We report here a case of an immunocompetent patient suffering from recurrent epithelial herpetic keratitis associated with the emergence of antiviral resistance. Indeed, the not previously described amino acid change L340R ...Lire la suite >
We report here a case of an immunocompetent patient suffering from recurrent epithelial herpetic keratitis associated with the emergence of antiviral resistance. Indeed, the not previously described amino acid change L340R within herpes simplex virus thymidine kinase, was shown to confer acyclovir-resistance by recombinant phenotyping using bacmid technology.< Réduire
Mots clés en anglais
herpes simplex virus
herpetic keratitis
antiviral resistance
recombinant virus
thymidine kinase
Unités de recherche