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Input of recombinant phenotyping for the characterization of a novel acyclovir- resistance mutation identified in a patient with recurrent herpetic keratitis
Language
EN
Article de revue
This item was published in
Antiviral Research. 2019, vol. 168, p. 183-186
English Abstract
We report here a case of an immunocompetent patient suffering from recurrent epithelial herpetic keratitis associated with the emergence of antiviral resistance. Indeed, the not previously described amino acid change L340R ...Read more >
We report here a case of an immunocompetent patient suffering from recurrent epithelial herpetic keratitis associated with the emergence of antiviral resistance. Indeed, the not previously described amino acid change L340R within herpes simplex virus thymidine kinase, was shown to confer acyclovir-resistance by recombinant phenotyping using bacmid technology.Read less <
English Keywords
herpes simplex virus
herpetic keratitis
antiviral resistance
recombinant virus
thymidine kinase