MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité)

L'objectif du laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP) est d'accroître les connaissances générales, scientifiques et fondamentales, sur les interactions entre des agents pathogènes (virus, bactéries, parasites et champignons) et leurs hôtes (mammifères et insectes vecteurs), liées à la réplication des microorganismes et au développement de la maladie. Le but final est de comprendre les conséquences des interactions moléculaires et métaboliques à différents niveaux, depuis les aspects les plus fondamentaux jusqu'à l’épidémiologie. Le laboratoire MFP est composé de 6 équipes dont les thèmes sont: "variabilité, réplication et mobilité des génomes viraux et bactériens", "dynamique intracellulaire des structures sous virales", "biogénèse du cytosquelette chez les trypanosomes", "métabolisme intermédiaire des trypanosomes", "Candida et pathogénicité" et "biologie moléculaire des machines bactériennes".

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MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234

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Recent Submissions

Intrabody-Induced Cell Death by Targeting the T. brucei Cytoskeletal Protein Tb BILBO1

SARS-CoV-2 transmission via apical syncytia release from primary bronchial epithelia and infectivity restriction in children epithelia

Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline

Targeting the Integrated Stress Response Kinase GCN2 to Modulate Retroviral Integration

Metabolic selection of a homologous recombination-mediated gene loss protects Trypanosoma brucei from ROS production by glycosomal fumarate reductase

Glycerol suppresses glucose consumption in trypanosomes through metabolic contest

Candida albicans Hexokinase 2 Challenges the Saccharomyces cerevisiae Moonlight Protein Model

Les méthodes de diagnostic des trypanosomiases animales africaines : avantages, limites et nouvelles pistes d’amélioration

Structural and functional studies of the first tripartite protein complex at the Trypanosoma brucei flagellar pocket collar

Feasibility of convalescent plasma therapy in severe COVID-19 patients with persistent SARS-CoV-2 viremia

In Silico, In Vitro and In Cellulo Models for Monitoring SARS-CoV-2 Spike/Human ACE2 Complex, Viral Entry and Cell Fusion

Efficient flavinylation of glycosomal fumarate reductase by its own ApbE domain in Trypanosoma brucei

Macromolecular interactions in vitro, comparing classical and novel approaches

Fatty acid oxidation participates in resistance to nutrient-depleted environments in the insect stages of Trypanosoma cruzi

Structural studies of the shortest extended synaptotagmin with only two C2 domains from Trypanosoma brucei

Cassette recruitment in the chromosomal Integron of Vibrio cholerae

Accuracy of COVID-19 rapid antigenic tests compared to RT-PCR in a student population: The StudyCov study

The kinesin of the flagellum attachment zone in Leishmania is required for cell morphogenesis, cell division and virulence in the mammalian host

Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase

The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place

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MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234

Browse by

Recent Submissions

Intrabody-Induced Cell Death by Targeting the T. brucei Cytoskeletal Protein Tb BILBO1 ﻿

SARS-CoV-2 transmission via apical syncytia release from primary bronchial epithelia and infectivity restriction in children epithelia ﻿

Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline ﻿

Targeting the Integrated Stress Response Kinase GCN2 to Modulate Retroviral Integration ﻿

Metabolic selection of a homologous recombination-mediated gene loss protects Trypanosoma brucei from ROS production by glycosomal fumarate reductase ﻿

Glycerol suppresses glucose consumption in trypanosomes through metabolic contest ﻿

Candida albicans Hexokinase 2 Challenges the Saccharomyces cerevisiae Moonlight Protein Model ﻿

Les méthodes de diagnostic des trypanosomiases animales africaines : avantages, limites et nouvelles pistes d’amélioration ﻿

Structural and functional studies of the first tripartite protein complex at the Trypanosoma brucei flagellar pocket collar ﻿

Feasibility of convalescent plasma therapy in severe COVID-19 patients with persistent SARS-CoV-2 viremia ﻿

In Silico, In Vitro and In Cellulo Models for Monitoring SARS-CoV-2 Spike/Human ACE2 Complex, Viral Entry and Cell Fusion ﻿

Efficient flavinylation of glycosomal fumarate reductase by its own ApbE domain in Trypanosoma brucei ﻿

Macromolecular interactions in vitro, comparing classical and novel approaches ﻿

Fatty acid oxidation participates in resistance to nutrient-depleted environments in the insect stages of Trypanosoma cruzi ﻿

Structural studies of the shortest extended synaptotagmin with only two C2 domains from Trypanosoma brucei ﻿

Cassette recruitment in the chromosomal Integron of Vibrio cholerae ﻿

Accuracy of COVID-19 rapid antigenic tests compared to RT-PCR in a student population: The StudyCov study ﻿

The kinesin of the flagellum attachment zone in Leishmania is required for cell morphogenesis, cell division and virulence in the mammalian host ﻿

Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase ﻿

The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place ﻿