MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234
L'objectif du laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP) est d'accroître les connaissances générales, scientifiques et fondamentales, sur les interactions entre des agents pathogènes (virus, bactéries, parasites et champignons) et leurs hôtes (mammifères et insectes vecteurs), liées à la réplication des microorganismes et au développement de la maladie. Le but final est de comprendre les conséquences des interactions moléculaires et métaboliques à différents niveaux, depuis les aspects les plus fondamentaux jusqu'à l’épidémiologie. Le laboratoire MFP est composé de 6 équipes dont les thèmes sont: "variabilité, réplication et mobilité des génomes viraux et bactériens", "dynamique intracellulaire des structures sous virales", "biogénèse du cytosquelette chez les trypanosomes", "métabolisme intermédiaire des trypanosomes", "Candida et pathogénicité" et "biologie moléculaire des machines bactériennes".
Browse by
Recent Submissions
-
Visualization of Trypanosoma brucei flagellar pocket collar biogenesis identifies two new cytoskeletal structures.
(PLoS Biology. vol. 23, n° 10, pp. e3003429, 2025-10-09)Article de revueOpen access -
Mucosal passive immunization with monoclonal antibodies targeting Candidalysin and Hyr proteins attenuates vaginal candidiasis in mice.
(Virulence. vol. 16, n° 1, pp. 2569629, 2025-12-01)Article de revueOpen access -
Development of chimeric multivalent proteins for serological diagnosis of African animal trypanosomosis.
(Parasitology. pp. 1-36, 2025-09-30)Article de revueOpen access -
Novel Thiazolidinedione Derivatives as Potential ZIKV Antiviral Inhibitors.
(Microorganisms. vol. 13, n° 9, 2025-08-22)Article de revueOpen access -
Aquarius helicase facilitates HIV-1 integration into R-loop enriched genomic regions.
(Nature Microbiology, 2025-08-20)Article de revue -
An Integrative Approach to Assessing the Impact of Mercury (Hg) on Avian Behaviour: From Molecule to Movement.
(Journal of Xenobiotics. vol. 15, n° 4, 2025-07-09)Article de revueOpen access -
G-quadruplexes are promoter elements controlling nucleosome exclusion and RNA polymerase II pausing.
(Nature Genetics. vol. 57, n° 8, pp. 1981-1993, 2025-08-01)Article de revue -
High-risk human papillomavirus cervical infection prevalence: a nationwide retrospective study comparing opportunistic and organised screening, France, 2020 to 2023
(Eurosurveillance. vol. 30, n° 28, pp. 2400689, 2025-07-17)Article de revue -
Isolation of New Chemical Modulators of the Interaction Between HIV-1 Integrase and the Cellular Restriction Factor GCN2.
(Viruses. vol. 17, n° 8, 2025-08-20)Article de revueOpen access -
Human Type-I Interferon Omega Holds Potent Antiviral Properties and Promotes Cytolytic CD8 T Cell Responses.
(European Journal of Immunology. vol. 55, n° 7, pp. e70003, 2025-07-01)Article de revue -
Lysosomal membrane permeabilization enhances the anticancer effects of POLR1 (RNA polymerase I) transcription inhibitors.
(Autophagy. pp. 1-20, 2025-06-18)Article de revue -
Interaction with eukaryotic cells enhances the circularization and transcription of integrative and conjugative elements in Mycoplasma hominis.
(Mobile DNA. vol. 16, n° 1, pp. 26, 2025-07-04)Article de revueOpen access -
CXCL10-dependent epithelial-vascular cross-talk for endothelial activation following SARS-CoV-2 infection.
(Scientific Reports. vol. 15, n° 1, pp. 21129, 2025-07-01)Article de revueOpen access -
Clinical evaluation of two commercial PCR kits for the detection of nonviral sexually transmitted infections.
(Journal of Medical Microbiology. vol. 74, n° 7, 2025-07-01)Article de revueOpen access -
Real-time genome imaging of host interactions in adeno-associated virus genome release.
(iScience. vol. 28, n° 6, pp. 112624, 2025-06-20)Article de revueOpen access -
Timed chromatin invasion during mitosis governs prototype foamy virus integration site selection and infectivity.
(Nucleic Acids Research. vol. 53, n° 10, 2025-05-22)Article de revueOpen access -
The glycosomal ATP-dependent phosphofructokinase of Trypanosoma brucei operates also in the gluconeogenic direction.
(PLoS Biology. vol. 23, n° 5, pp. e3002938, 2025-05-16)Article de revueOpen access -
LAVR-289, an Orally Bioavailable Inhibitor of Adenovirus Replication In Vitro and In Vivo
(ACS Infectious Diseases, 2025-05-19)Article de revue -
Advanced viral genome in vitro Cas9 editing (AdVICE): an overnight method for traceless and limitless manipulation of adenoviral and vector genomes with large transgenes
(Journal of Virology. pp. e0226524, 2025-05-21)Article de revueOpen access -
Doxycycline en prévention des infections sexuellement transmissibles, pratiques d’utilisation : revue narrative de la littérature
(Santé Publique. vol. 37, n° 1, pp. 119-129, 2025-01-01)Article de revue
Statistics
Collection General Statistics
Typology History
| 2021 | 2022 | 2023 | 2024 | 2025 | |
|---|---|---|---|---|---|
| Actes de congrès/Proceedings | 0 | 0 | 0 | 0 | 0 |
| Article de blog scientifique | 0 | 0 | 0 | 0 | 0 |
| Article de revue | 40 | 45 | 35 | 38 | 35 |
| Autre document | 0 | 0 | 0 | 0 | 0 |
| Brevet | 0 | 0 | 0 | 0 | 0 |
| Chapitre d'ouvrage | 0 | 0 | 0 | 0 | 0 |
| Communication dans un congrès | 0 | 0 | 0 | 0 | 0 |
| Document de travail - Pré-publication | 0 | 2 | 0 | 0 | 0 |
| HDR | 0 | 0 | 0 | 0 | 0 |
| Notice d'encyclopédie ou de dictionnaire | 0 | 0 | 0 | 0 | 0 |
| N°spécial de revue/special issue | 0 | 0 | 0 | 0 | 0 |
| Ouvrage | 0 | 0 | 0 | 0 | 0 |
| Poster | 0 | 0 | 0 | 0 | 0 |
| Rapport | 0 | 0 | 0 | 0 | 0 |
| Thèse d'exercice | 0 | 0 | 0 | 0 | 0 |
| Thèses de doctorat | 3 | 1 | 0 | 0 | 0 |
| Traduction | 0 | 0 | 0 | 0 | 0 |