MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité)

L'objectif du laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP) est d'accroître les connaissances générales, scientifiques et fondamentales, sur les interactions entre des agents pathogènes (virus, bactéries, parasites et champignons) et leurs hôtes (mammifères et insectes vecteurs), liées à la réplication des microorganismes et au développement de la maladie. Le but final est de comprendre les conséquences des interactions moléculaires et métaboliques à différents niveaux, depuis les aspects les plus fondamentaux jusqu'à l’épidémiologie. Le laboratoire MFP est composé de 6 équipes dont les thèmes sont: "variabilité, réplication et mobilité des génomes viraux et bactériens", "dynamique intracellulaire des structures sous virales", "biogénèse du cytosquelette chez les trypanosomes", "métabolisme intermédiaire des trypanosomes", "Candida et pathogénicité" et "biologie moléculaire des machines bactériennes".

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MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234

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Recent Submissions

Human Type-I Interferon Omega Holds Potent Antiviral Properties and Promotes Cytolytic CD8 T Cell Responses.

Lysosomal membrane permeabilization enhances the anticancer effects of POLR1 (RNA polymerase I) transcription inhibitors.

Interaction with eukaryotic cells enhances the circularization and transcription of integrative and conjugative elements in Mycoplasma hominis.

CXCL10-dependent epithelial-vascular cross-talk for endothelial activation following SARS-CoV-2 infection.

Clinical evaluation of two commercial PCR kits for the detection of nonviral sexually transmitted infections.

Real-time genome imaging of host interactions in adeno-associated virus genome release.

Timed chromatin invasion during mitosis governs prototype foamy virus integration site selection and infectivity.

The glycosomal ATP-dependent phosphofructokinase of Trypanosoma brucei operates also in the gluconeogenic direction.

LAVR-289, an Orally Bioavailable Inhibitor of Adenovirus Replication In Vitro and In Vivo

Advanced viral genome in vitro Cas9 editing (AdVICE): an overnight method for traceless and limitless manipulation of adenoviral and vector genomes with large transgenes

Doxycycline en prévention des infections sexuellement transmissibles, pratiques d’utilisation : revue narrative de la littérature

Room temperature storage and shipping of encapsulated synthetic RNAs as quality control materials for SARS-CoV-2 molecular diagnostic assays.

Endovascular management of pelvic congestion syndrome: An expert consensus statement from the French Society of Cardiovascular Imaging (SFICV), Interventional Radiology Federation (FRI), College of French Radiology Teachers (CERF), and French Society of Women's Imaging (SIFEM).

High anal Chlamydia trachomatis load is associated with LGV and symptoms in MSM: Results of a cross-sectional study.

Vancomycin versus linezolid for treatment of staphylococcal-associated central nervous system infections

Recommandations pour la pratique clinique : prévention et prise en charge de l’infection par le virus varicelle zona (VZV) pendant la grossesse et la période périnatale (version longue)

Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis

A new member of the dynamin superfamily modulates mitochondrial membrane branching in Trypanosoma brucei.

The role of l-serine and l-threonine in the energy metabolism and nutritional stress response of Trypanosoma cruzi .

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis.

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MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234

Browse by

Recent Submissions

Human Type-I Interferon Omega Holds Potent Antiviral Properties and Promotes Cytolytic CD8 T Cell Responses. ﻿

Lysosomal membrane permeabilization enhances the anticancer effects of POLR1 (RNA polymerase I) transcription inhibitors. ﻿

Interaction with eukaryotic cells enhances the circularization and transcription of integrative and conjugative elements in Mycoplasma hominis. ﻿

CXCL10-dependent epithelial-vascular cross-talk for endothelial activation following SARS-CoV-2 infection. ﻿

Clinical evaluation of two commercial PCR kits for the detection of nonviral sexually transmitted infections. ﻿

Real-time genome imaging of host interactions in adeno-associated virus genome release. ﻿

Timed chromatin invasion during mitosis governs prototype foamy virus integration site selection and infectivity. ﻿

The glycosomal ATP-dependent phosphofructokinase of Trypanosoma brucei operates also in the gluconeogenic direction. ﻿

LAVR-289, an Orally Bioavailable Inhibitor of Adenovirus Replication In Vitro and In Vivo ﻿

Advanced viral genome in vitro Cas9 editing (AdVICE): an overnight method for traceless and limitless manipulation of adenoviral and vector genomes with large transgenes ﻿

Doxycycline en prévention des infections sexuellement transmissibles, pratiques d’utilisation : revue narrative de la littérature ﻿

Room temperature storage and shipping of encapsulated synthetic RNAs as quality control materials for SARS-CoV-2 molecular diagnostic assays. ﻿

Endovascular management of pelvic congestion syndrome: An expert consensus statement from the French Society of Cardiovascular Imaging (SFICV), Interventional Radiology Federation (FRI), College of French Radiology Teachers (CERF), and French Society of Women's Imaging (SIFEM). ﻿

High anal Chlamydia trachomatis load is associated with LGV and symptoms in MSM: Results of a cross-sectional study. ﻿

Vancomycin versus linezolid for treatment of staphylococcal-associated central nervous system infections ﻿

Recommandations pour la pratique clinique : prévention et prise en charge de l’infection par le virus varicelle zona (VZV) pendant la grossesse et la période périnatale (version longue) ﻿

Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis ﻿

A new member of the dynamin superfamily modulates mitochondrial membrane branching in Trypanosoma brucei. ﻿

The role of l-serine and l-threonine in the energy metabolism and nutritional stress response of Trypanosoma cruzi . ﻿

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis. ﻿