MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234
L'objectif du laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP) est d'accroître les connaissances générales, scientifiques et fondamentales, sur les interactions entre des agents pathogènes (virus, bactéries, parasites et champignons) et leurs hôtes (mammifères et insectes vecteurs), liées à la réplication des microorganismes et au développement de la maladie. Le but final est de comprendre les conséquences des interactions moléculaires et métaboliques à différents niveaux, depuis les aspects les plus fondamentaux jusqu'à l’épidémiologie. Le laboratoire MFP est composé de 6 équipes dont les thèmes sont: "variabilité, réplication et mobilité des génomes viraux et bactériens", "dynamique intracellulaire des structures sous virales", "biogénèse du cytosquelette chez les trypanosomes", "métabolisme intermédiaire des trypanosomes", "Candida et pathogénicité" et "biologie moléculaire des machines bactériennes".
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Recent Submissions
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Timed chromatin invasion during mitosis governs prototype foamy virus integration site selection and infectivity.
(Nucleic Acids Research. vol. 53, n° 10, 2025-05-22)Article de revueOpen access -
The glycosomal ATP-dependent phosphofructokinase of Trypanosoma brucei operates also in the gluconeogenic direction.
(PLoS Biology. vol. 23, n° 5, pp. e3002938, 2025-05-16)Article de revueOpen access -
LAVR-289, an Orally Bioavailable Inhibitor of Adenovirus Replication In Vitro and In Vivo
(ACS Infectious Diseases, 2025-05-19)Article de revue -
Advanced viral genome in vitro Cas9 editing (AdVICE): an overnight method for traceless and limitless manipulation of adenoviral and vector genomes with large transgenes
(Journal of Virology. pp. e0226524, 2025-05-21)Article de revueOpen access -
Doxycycline en prévention des infections sexuellement transmissibles, pratiques d’utilisation : revue narrative de la littérature
(Santé Publique. vol. 37, n° 1, pp. 119-129, 2025-01-01)Article de revue -
Room temperature storage and shipping of encapsulated synthetic RNAs as quality control materials for SARS-CoV-2 molecular diagnostic assays.
(Journal of Virological Methods. pp. 115169, 2025-04-25)Article de revue -
Endovascular management of pelvic congestion syndrome: An expert consensus statement from the French Society of Cardiovascular Imaging (SFICV), Interventional Radiology Federation (FRI), College of French Radiology Teachers (CERF), and French Society of Women's Imaging (SIFEM).
(Diagnostic and Interventional Imaging, 2025-04-30)Article de revue -
High anal Chlamydia trachomatis load is associated with LGV and symptoms in MSM: Results of a cross-sectional study.
(Journal of the European Academy of Dermatology and Venereology, 2025-05-02)Article de revue -
Vancomycin versus linezolid for treatment of staphylococcal-associated central nervous system infections
(BMC Infectious Diseases. vol. 25, n° 1, pp. 446, 2025-03-31)Article de revueOpen access -
Recommandations pour la pratique clinique : prévention et prise en charge de l’infection par le virus varicelle zona (VZV) pendant la grossesse et la période périnatale (version longue)
(Gynécologie Obstétrique Fertilité & Sénologie. vol. 53, n° 3, pp. 118-129, 2025-01-11)Article de revue -
Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis
(PLoS Medicine. vol. 12, n° 4, pp. e1001810, 2015)Article de revueOpen access -
A new member of the dynamin superfamily modulates mitochondrial membrane branching in Trypanosoma brucei.
(Current Biology, 2025-03-06)Article de revueOpen access -
The role of l-serine and l-threonine in the energy metabolism and nutritional stress response of Trypanosoma cruzi .
(MSphere. pp. e0098324, 2025-03-05)Article de revueOpen access -
Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis.
(PLoS Medicine. vol. 12, n° 4, pp. e1001810, 2015-04-01)Article de revueOpen access -
Unexpected increase in ompA-genotype L1 variants responsible for anorectal lymphogranuloma venereum in France.
(The Lancet Microbe. pp. 101097, 2025-02-25)Article de revueOpen access -
Safety of high-dose daptomycin in obese patients: a multicentric retrospective study.
(European Journal of Clinical Microbiology and Infectious Diseases, 2025-02-24)Article de revue -
Mycoplasma pneumoniae infection in adult inpatients during the 2023-24 outbreak in France (MYCADO): a national, retrospective, observational study.
(The Lancet Infectious Diseases, 2025-02-19)Article de revue -
Association between herpes simplex virus infection and Alzheimer's disease biomarkers: analysis within the MAPT trial
(Scientific Reports. vol. 15, n° 1, pp. 2362, 2025-01-18)Article de revueOpen access -
Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly
(Nature Communications. vol. 15, n° 1, pp. 640, 2024-01-20)Article de revue -
Receptor-recognition and antiviral mechanisms of retrovirus-derived human proteins
(Nature Structural and Molecular Biology. vol. 31, n° 9, pp. 1368 - 1376, 2024-09)Article de revue
Statistics
Collection General Statistics
Typology History
2021 | 2022 | 2023 | 2024 | 2025 | |
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Actes de congrès/Proceedings | 0 | 0 | 0 | 0 | 0 |
Article de blog scientifique | 0 | 0 | 0 | 0 | 0 |
Article de revue | 40 | 45 | 35 | 38 | 20 |
Autre document | 0 | 0 | 0 | 0 | 0 |
Brevet | 0 | 0 | 0 | 0 | 0 |
Chapitre d'ouvrage | 0 | 0 | 0 | 0 | 0 |
Communication dans un congrès | 0 | 0 | 0 | 0 | 0 |
Document de travail - Pré-publication | 0 | 2 | 0 | 0 | 0 |
HDR | 0 | 0 | 0 | 0 | 0 |
Notice d'encyclopédie ou de dictionnaire | 0 | 0 | 0 | 0 | 0 |
N°spécial de revue/special issue | 0 | 0 | 0 | 0 | 0 |
Ouvrage | 0 | 0 | 0 | 0 | 0 |
Poster | 0 | 0 | 0 | 0 | 0 |
Rapport | 0 | 0 | 0 | 0 | 0 |
Thèse d'exercice | 0 | 0 | 0 | 0 | 0 |
Thèses de doctorat | 3 | 1 | 0 | 0 | 0 |
Traduction | 0 | 0 | 0 | 0 | 0 |