MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité)

L'objectif du laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP) est d'accroître les connaissances générales, scientifiques et fondamentales, sur les interactions entre des agents pathogènes (virus, bactéries, parasites et champignons) et leurs hôtes (mammifères et insectes vecteurs), liées à la réplication des microorganismes et au développement de la maladie. Le but final est de comprendre les conséquences des interactions moléculaires et métaboliques à différents niveaux, depuis les aspects les plus fondamentaux jusqu'à l’épidémiologie. Le laboratoire MFP est composé de 6 équipes dont les thèmes sont: "variabilité, réplication et mobilité des génomes viraux et bactériens", "dynamique intracellulaire des structures sous virales", "biogénèse du cytosquelette chez les trypanosomes", "métabolisme intermédiaire des trypanosomes", "Candida et pathogénicité" et "biologie moléculaire des machines bactériennes".

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MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234

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Envíos recientes

Integrase-LEDGF/p75 complex triggers the formation of biomolecular condensates that modulate HIV-1 integration efficiency in vitro.

Prevention and management of VZV infection during pregnancy and the perinatal period.

Isolation and Characterization of Environmental Extended Spectrum β-Lactamase-Producing and from Ouagadougou, Burkina Faso.

Toxoplasma type II effector GRA15 has limited influence in vivo.

Sonicate Fluid Inoculation Into Blood Culture Bottles for Vascular Graft and Endograft Infection Microbiological Diagnosis.

An ex vivo study of infections of vascular grafts and endografts with scanning electron microscopy.

Bacteraemia associated with multiple septic localizations caused by Klebsiella pneumoniae sequence type ST660.

Activation of GCN2 upon HIV-1 infection and inhibition of translation.

Natural stilbenoids isolated from grapevine exhibiting inhibitory effects against HIV-1 integrase and eukaryote MOS1 transposase in vitro activities.

Investigation of a novel series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as human immunodeficiency virus type 1 integrase inhibitors.

Elucidating the Transport Mechanisms and Metabolic Roles of Serine, Threonine, and Glycine in Trypanosoma cruzi

In vitro analysis of the susceptibility of HIV-1 subtype A and CRF01_AE integrases to raltegravir.

Seroprevalence of human herpes viruses in France, 2018-2022: a multilevel regression and poststratification approach.

Factors predicting the spontaneous regression of cervical high-grade squamous intraepithelial lesions (HSIL/CIN2).

Regression of cervical high-grade squamous intraepithelial lesions (HSIL/CIN2) managed expectantly.

Fish consumption habits of pregnant women in Itaituba, Tapajós River basin, Brazil: risks of mercury contamination as assessed by measuring total mercury in highly consumed piscivore fish species and in hair of pregnant women.

Severe enterovirus infections in patients with immune-mediated inflammatory diseases receiving anti-CD20 monoclonal antibodies.

Structural insights into the mechanism of DNA branch migration during homologous recombination in bacteria.

Evaluation of commercial, customized microdilution plates for Ureaplasma parvum, Ureaplasma urealyticum, and Mycoplasma hominis antimicrobial susceptibility testing and determination of antimicrobial resistance prevalence in France

Prevalence of macrolide and fluoroquinolone resistance-associated mutations in in metropolitan and overseas France.

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MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234

Listar por

Envíos recientes

Integrase-LEDGF/p75 complex triggers the formation of biomolecular condensates that modulate HIV-1 integration efficiency in vitro. ﻿

Prevention and management of VZV infection during pregnancy and the perinatal period. ﻿

Isolation and Characterization of Environmental Extended Spectrum β-Lactamase-Producing and from Ouagadougou, Burkina Faso. ﻿

Toxoplasma type II effector GRA15 has limited influence in vivo. ﻿

Sonicate Fluid Inoculation Into Blood Culture Bottles for Vascular Graft and Endograft Infection Microbiological Diagnosis. ﻿

An ex vivo study of infections of vascular grafts and endografts with scanning electron microscopy. ﻿

Bacteraemia associated with multiple septic localizations caused by Klebsiella pneumoniae sequence type ST660. ﻿

Activation of GCN2 upon HIV-1 infection and inhibition of translation. ﻿

Natural stilbenoids isolated from grapevine exhibiting inhibitory effects against HIV-1 integrase and eukaryote MOS1 transposase in vitro activities. ﻿

Investigation of a novel series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as human immunodeficiency virus type 1 integrase inhibitors. ﻿

Elucidating the Transport Mechanisms and Metabolic Roles of Serine, Threonine, and Glycine in Trypanosoma cruzi ﻿

In vitro analysis of the susceptibility of HIV-1 subtype A and CRF01_AE integrases to raltegravir. ﻿

Seroprevalence of human herpes viruses in France, 2018-2022: a multilevel regression and poststratification approach. ﻿

Factors predicting the spontaneous regression of cervical high-grade squamous intraepithelial lesions (HSIL/CIN2). ﻿

Regression of cervical high-grade squamous intraepithelial lesions (HSIL/CIN2) managed expectantly. ﻿

Fish consumption habits of pregnant women in Itaituba, Tapajós River basin, Brazil: risks of mercury contamination as assessed by measuring total mercury in highly consumed piscivore fish species and in hair of pregnant women. ﻿

Severe enterovirus infections in patients with immune-mediated inflammatory diseases receiving anti-CD20 monoclonal antibodies. ﻿

Structural insights into the mechanism of DNA branch migration during homologous recombination in bacteria. ﻿

Evaluation of commercial, customized microdilution plates for Ureaplasma parvum, Ureaplasma urealyticum, and Mycoplasma hominis antimicrobial susceptibility testing and determination of antimicrobial resistance prevalence in France ﻿

Prevalence of macrolide and fluoroquinolone resistance-associated mutations in in metropolitan and overseas France. ﻿