Metadatos
Mostrar el registro completo del ítemCompartir este ítem
Input of recombinant phenotyping for the characterization of a novel acyclovir- resistance mutation identified in a patient with recurrent herpetic keratitis
Idioma
EN
Article de revue
Este ítem está publicado en
Antiviral Research. 2019, vol. 168, p. 183-186
Resumen en inglés
We report here a case of an immunocompetent patient suffering from recurrent epithelial herpetic keratitis associated with the emergence of antiviral resistance. Indeed, the not previously described amino acid change L340R ...Leer más >
We report here a case of an immunocompetent patient suffering from recurrent epithelial herpetic keratitis associated with the emergence of antiviral resistance. Indeed, the not previously described amino acid change L340R within herpes simplex virus thymidine kinase, was shown to confer acyclovir-resistance by recombinant phenotyping using bacmid technology.< Leer menos
Palabras clave en inglés
herpes simplex virus
herpetic keratitis
antiviral resistance
recombinant virus
thymidine kinase
Centros de investigación