Input of recombinant phenotyping for the characterization of a novel acyclovir- resistance mutation identified in a patient with recurrent herpetic keratitis
dc.rights.license | open | en_US |
hal.structure.identifier | Centre Hospitalier Universitaire de Bordeaux [CHU Bordeaux] | |
dc.contributor.author | ROBINET-PERRIN, Antoine | |
hal.structure.identifier | Microbiologie Fondamentale et Pathogénicité [MFP] | |
dc.contributor.author | TUMIOTTO, Camille | |
hal.structure.identifier | Centre Hospitalier Universitaire de Bordeaux [CHU Bordeaux] | |
dc.contributor.author | CORNUT, Thomas | |
hal.structure.identifier | Centre Hospitalier Universitaire de Bordeaux [CHU Bordeaux] | |
dc.contributor.author | SANTONI, Alexandra | |
hal.structure.identifier | Centre Hospitalier Universitaire de Bordeaux [CHU Bordeaux] | |
dc.contributor.author | TOUBOUL, David | |
dc.contributor.author | GOUPIL-GOUYETTE, Thibaud | |
hal.structure.identifier | Microbiologie Fondamentale et Pathogénicité [MFP] | |
dc.contributor.author | GARRIGUE, Isabelle
IDREF: 12258953X | |
dc.contributor.author | BOUTOLLEAU, David | |
dc.contributor.author | BURREL, Sonia | |
dc.date.accessioned | 2023-06-14T10:24:35Z | |
dc.date.available | 2023-06-14T10:24:35Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 0166-3542 | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/182680 | |
dc.description.abstractEn | We report here a case of an immunocompetent patient suffering from recurrent epithelial herpetic keratitis associated with the emergence of antiviral resistance. Indeed, the not previously described amino acid change L340R within herpes simplex virus thymidine kinase, was shown to confer acyclovir-resistance by recombinant phenotyping using bacmid technology. | |
dc.language.iso | EN | en_US |
dc.subject.en | herpes simplex virus | |
dc.subject.en | herpetic keratitis | |
dc.subject.en | antiviral resistance | |
dc.subject.en | recombinant virus | |
dc.subject.en | thymidine kinase | |
dc.title.en | Input of recombinant phenotyping for the characterization of a novel acyclovir- resistance mutation identified in a patient with recurrent herpetic keratitis | |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1016/j.antiviral.2019.06.007 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Maladies infectieuses | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Dermatologie | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Microbiologie et Parasitologie/Virologie | en_US |
bordeaux.journal | Antiviral Research | en_US |
bordeaux.page | 183-186 | en_US |
bordeaux.volume | 168 | en_US |
bordeaux.hal.laboratories | MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234 | en_US |
bordeaux.institution | CNRS | en_US |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
bordeaux.import.source | hal | |
hal.identifier | hal-02314044 | |
hal.version | 1 | |
hal.export | false | |
workflow.import.source | hal | |
dc.rights.cc | Pas de Licence CC | en_US |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Antiviral%20Research&rft.date=2019&rft.volume=168&rft.spage=183-186&rft.epage=183-186&rft.eissn=0166-3542&rft.issn=0166-3542&rft.au=ROBINET-PERRIN,%20Antoine&TUMIOTTO,%20Camille&CORNUT,%20Thomas&SANTONI,%20Alexandra&TOUBOUL,%20David&rft.genre=article |