OGURA, Kota; BRASSELET, Clément; CABRERA-BARJAS, Gustavo; HAMIDI, Masoud; SHAVANDI, Amin; DOLS-LAFARGUE, Marguerite; SAWAMURA, Naoki; DELATTRE, Cédric

doi:10.3390/ma15041375

Langue

Article de revue

Ce document a été publié dans

Materials. 2022-02, vol. 15, n° 4, p. 1375

Résumé en anglais

In this present work, fungal nanochitosans, with very interesting particle size distribution of 22 µm, were efficiently generated in high-yield production using a high-pressure water jet system (Star Burst System, Sugino, Japan) after 10 passes of mechanical treatment under high pressure. The specific characterization of fungal chitosan nanofibers suspensions in water revealed a high viscosity of 1450 mPa.s and an estimated transparency of 43.5% after 10 passes of fibrillation mechanical treatment. The mechanical characterization of fungal nanochitosan (NC) film are very interesting for medical applications with a Young’s modulus (E), a tensile strength (TS), and elongation at break (e%) estimated at 2950 MPa, 50.5 MPa, and 5.5%, respectively. Furthermore, we exhibited that the fungal nanochitosan (NC) film presented very good long-term antioxidant effect (reached 82.4% after 96 h of contact with DPPH radical solution) and very interesting antimicrobial activity when the nanochitosan (NC) fibers are mainly activated as NC-NH3+ form at the surface of the film with 45% reduction and 75% reduction observed for S. aureus (Gram-positive) and E. coli (Gram-negative), respectively, after 6 h of treatment. These promising antimicrobial and antioxidant activities indicated the high potential of valorization toward biomedical applications.< Réduire

Mots clés en anglais

fungal chitosan

nanofiber

high-pressure water jet system

antimicrobial film

antioxidant film

URI

https://oskar-bordeaux.fr/handle/20.500.12278/140307

DOI

http://dx.doi.org/10.3390/ma15041375

Project ANR

Recherches sur l'origine et les effets secondaires des propriétés stabilisantes du chitosane fongique dans le vin - ANR-17-CE21-0006

Unités de recherche

Oenologie - UMR 1366

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Production of Fungal Nanochitosan Using High-Pressure Water Jet System for Biomedical Applications