MONTIBUS, Mathilde; VITRAC, Xavier; COMA, Veronique; LORON, Anne; LORON, A.; PINSON-GADAIS, Laetitia; FERRER, Nathalie; VERDAL-BONNIN, Marie-Noëlle; GABASTON, Julien; WAFFO TEGUO, Pierre; RICHARD-FORGET, Florence; ATANASOVA-PENICHON, Vessela

doi:10.3390/molecules26020405

MONTIBUS, Mathilde
Institut Technologique Forêt Cellulose Bois-construction Ameublement [FCBA]

VITRAC, Xavier

COMA, Veronique

Laboratoire de Chimie des Polymères Organiques [LCPO]

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Article de revue

Ce document a été publié dans

Molecules. 2021, vol. 26, n° 2

Résumé en anglais

Fusarium graminearum is a fungal pathogen that can colonize small-grain cereals and maize and secrete type B trichothecene (TCTB) mycotoxins. The development of environmental-friendly strategies guaranteeing the safety of food and feed is a key challenge facing agriculture today. One of these strategies lies on the promising capacity of products issued from natural sources to counteract crop pests. In this work, the in vitro efficiency of sixteen extracts obtained from eight natural sources using subcritical water extraction at two temperatures was assessed against fungal growth and TCTB production by F. graminearum. Maritime pine sawdust extract was shown to be extremely efficient, leading to a significant inhibition of up to 89% of the fungal growth and up to 65% reduction of the mycotoxin production by F. graminearum. Liquid chromatography/mass spectrometry analysis of this active extract revealed the presence of three families of phenolics with a predominance of methylated compounds and suggested that the abundance of methylated structures, and therefore of hydrophobic compounds, could be a primary factor underpinning the activity of the maritime pine sawdust extract. Altogether, our data support that wood/forest by-products could be promising sources of bioactive compounds for controlling F. graminearum and its production of mycotoxins.< Réduire

Mots clés en anglais

Fusarium graminearum

Type B trichothecenes

Natural extracts

Ecological strategies

Biofungicides

URI

https://oskar-bordeaux.fr/handle/20.500.12278/128747

DOI

http://dx.doi.org/10.3390/molecules26020405

Project ANR

Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation - ANR-11-INBS-0010

Unités de recherche

Oenologie - UMR 1366

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Screening of wood/forest and vine by-products as sources of new drugs for sustainable strategies to control fusarium graminearum and the production of mycotoxins