A review of dietary stilbenes: sources and bioavailability
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EN
Article de revue
Este ítem está publicado en
Phytochemistry Reviews. 2018, vol. 17, n° 5, p. 1007-1029
Resumen en inglés
Stilbenes are a class of phenolic metabolites found in various edible plants, such as grapevine, berries and peanuts. Their bioactivitiy and their potential benefits for human health have been the subject of several studies. ...Leer más >
Stilbenes are a class of phenolic metabolites found in various edible plants, such as grapevine, berries and peanuts. Their bioactivitiy and their potential benefits for human health have been the subject of several studies. Among all identified stilbenes, resveratrol has been particularly studied and results from literature showed that it presents several biological activities, including antioxidant, anti-inflammatory and antiproliferative effects. Likewise, some researches focused on other stilbenes and highlighted similar biological activity for those compounds. However, stilbenes present a high diversity in their phenolic structures (various chemical substituents and polymerization) which is a determining factor of their absorption and metabolism rates. Consequently, this could affect the effectiveness of stilbenes in vivo. In this context, an evaluation of the bioavailability and metabolism of stilbenes is necessary to move forward with pharmacological and clinical studies. Hence, this review aims to present recently obtained data and results concerning stilbenes sources and bioavailability, as a contribution to the valorization of the role of dietary stilbenes in the human diet.< Leer menos
Palabras clave
Pharmacocinétique
Stilbene
Metabolite
Alimentation humaine
Palabras clave en inglés
Bioavailability
Metabolism
Pharmacokinetics
Stilbenes
Centros de investigación