Investigation of Low-Energy Proton Effects on Aptamer Performance for Astrobiological Applications
LE POSTOLLEC, A.
Laboratoire d'Astrophysique de Bordeaux [Pessac] [LAB]
Observatoire aquitain des sciences de l'univers [OASU]
Université Sciences et Technologies - Bordeaux 1 [UB]
Laboratoire d'astrodynamique, d'astrophysique et d'aéronomie de bordeaux [L3AB]
See more >
Laboratoire d'Astrophysique de Bordeaux [Pessac] [LAB]
Observatoire aquitain des sciences de l'univers [OASU]
Université Sciences et Technologies - Bordeaux 1 [UB]
Laboratoire d'astrodynamique, d'astrophysique et d'aéronomie de bordeaux [L3AB]
LE POSTOLLEC, A.
Laboratoire d'Astrophysique de Bordeaux [Pessac] [LAB]
Observatoire aquitain des sciences de l'univers [OASU]
Université Sciences et Technologies - Bordeaux 1 [UB]
Laboratoire d'astrodynamique, d'astrophysique et d'aéronomie de bordeaux [L3AB]
Laboratoire d'Astrophysique de Bordeaux [Pessac] [LAB]
Observatoire aquitain des sciences de l'univers [OASU]
Université Sciences et Technologies - Bordeaux 1 [UB]
Laboratoire d'astrodynamique, d'astrophysique et d'aéronomie de bordeaux [L3AB]
DOBRIJEVIC, M.
Laboratoire d'Astrophysique de Bordeaux [Pessac] [LAB]
Observatoire aquitain des sciences de l'univers [OASU]
Université Sciences et Technologies - Bordeaux 1 [UB]
Laboratoire d'astrodynamique, d'astrophysique et d'aéronomie de bordeaux [L3AB]
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Laboratoire d'Astrophysique de Bordeaux [Pessac] [LAB]
Observatoire aquitain des sciences de l'univers [OASU]
Université Sciences et Technologies - Bordeaux 1 [UB]
Laboratoire d'astrodynamique, d'astrophysique et d'aéronomie de bordeaux [L3AB]
Language
en
Article de revue
This item was published in
Astrobiology. 2011, vol. 11, p. 207-211
Mary Ann Liebert
English Abstract
Biochips are promising instruments for the search for organic molecules in planetary environments. Nucleic acid aptamers are powerful affinity receptors known for their high affinity and specificity, and therefore are of ...Read more >
Biochips are promising instruments for the search for organic molecules in planetary environments. Nucleic acid aptamers are powerful affinity receptors known for their high affinity and specificity, and therefore are of great interest for space biochip development. A wide variety of aptamers have already been selected toward targets of astrobiological interest (from amino acids to microorganisms). We present a first study to test the resistance of these receptors to the constraints of the space environment. The emphasis is on the effect of cosmic rays on the molecular recognition properties of DNA aptamers. Experiments on beam-line facilities have been conducted with 2 MeV protons and fluences much higher than expected for a typical mission to Mars. Our results show that this irradiation process did not affect the performances of DNA aptamers as molecular recognition tools.Read less <
English Keywords
Aptamer
Biochip
Microarray
Cosmic radiation
Origin
Hal imported