GOMEZ-LOPEZ, Iván; ESEBERRI, Itziar; KRISA, Stéphanie; CANO, M. Pilar; PORTILLO, María P

doi:10.3390/plants13212967

KRISA, Stéphanie
Unité de Recherche Œnologie [Villenave d'Ornon] [OENO]

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Article de revue

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Plants. 2024-10-24, vol. 13, n° 21, p. 2967

Resumen en inglés

Opuntia stricta var. dillenii, a member of the Cactaceae family, produces a fruit known as prickly pear. This fruit is rich in bioactive compounds, including betalains and phenolic compounds, which play an important role in health promotion due to their antioxidant and anti-inflammatory properties. This study aims to investigate the impact of prickly pear extracts obtained from the whole fruit, peel, pulp, and an industrial by-product (bagasse) on the differentiation of 3T3-L1 pre-adipocytes. During the differentiation process, 3T3-L1 pre-adipocytes were treated with prickly pear extracts at concentrations ranging from 10 to 100 μg/mL from day 0 to day 8 post-induction. Moreover, the potential mechanisms justifying the observed effects were assessed by RT-PCR. All extracts led to an increase in both triacylglycerol accumulation and cell number. In conclusion, the analysed extracts demonstrated adipogenic effects in 3T3-L1 maturing pre-adipocytes by increasing the expression of the c/ebp-β, srebf-1, and c/ebp-α genes. Additionally, a potential anti-inflammatory effect was observed through the upregulation of adiponectin. © 2024 by the authors.< Leer menos

Palabras clave en inglés

3t3-L1 Pre-Adipocytes

Adipogenesis

Adiponectin

Betalains

Opuntia Stricta Var. Dillenii

Phenolic Compounds

Triacylglycerol

URI

https://oskar-bordeaux.fr/handle/20.500.12278/206001

DOI

http://dx.doi.org/10.3390/plants13212967

Link to research data

https: //www.mdpi.com/article/10.3390/plants13212967/s1

Centros de investigación

Oenologie - UMR 1366

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Effects of Opuntia stricta var. dillenii Extracts Obtained from Prickly Pear and an Industrial By-Product on Maturing Pre-Adipocytes