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Redefining common and rare HTRA1 variants as risk factors for polyvascular disease
Language
EN
Article de revue
This item was published in
Nature Cardiovascular Research. 2024-06-01, vol. 3, n° 6, p. 619-621
English Abstract
Rare and common variants in HTRA1 are associated with ischemic stroke. Research now sheds light on the underlying genetic architecture and suggests a vasculopathy with a broader phenotypic spectrum. Lower HTRA1 protease ...Read more >
Rare and common variants in HTRA1 are associated with ischemic stroke. Research now sheds light on the underlying genetic architecture and suggests a vasculopathy with a broader phenotypic spectrum. Lower HTRA1 protease activity and circulating levels both predict an increased risk of ischemic stroke and coronary artery disease.Read less <