Redefining common and rare HTRA1 variants as risk factors for polyvascular disease
dc.rights.license | open | en_US |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | DEBETTE, Stephanie | |
dc.contributor.author | IHARA, Masafumi | |
dc.date.accessioned | 2024-08-23T09:49:11Z | |
dc.date.available | 2024-08-23T09:49:11Z | |
dc.date.issued | 2024-06-01 | |
dc.identifier.issn | 2731-0590 | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/201286 | |
dc.description.abstractEn | Rare and common variants in HTRA1 are associated with ischemic stroke. Research now sheds light on the underlying genetic architecture and suggests a vasculopathy with a broader phenotypic spectrum. Lower HTRA1 protease activity and circulating levels both predict an increased risk of ischemic stroke and coronary artery disease. | |
dc.language.iso | EN | en_US |
dc.title.en | Redefining common and rare HTRA1 variants as risk factors for polyvascular disease | |
dc.title.alternative | Nat Cardiovasc Res | en_US |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1038/s44161-024-00492-2 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
bordeaux.journal | Nature Cardiovascular Research | en_US |
bordeaux.page | 619-621 | en_US |
bordeaux.volume | 3 | en_US |
bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
bordeaux.issue | 6 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.institution | INSERM | en_US |
bordeaux.team | ELEANOR_BPH | en_US |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
hal.identifier | hal-04676170 | |
hal.version | 1 | |
hal.date.transferred | 2024-08-23T09:49:13Z | |
hal.popular | non | en_US |
hal.audience | Internationale | en_US |
hal.export | true | |
dc.rights.cc | Pas de Licence CC | en_US |
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