Redefining common and rare HTRA1 variants as risk factors for polyvascular disease
Langue
EN
Article de revue
Ce document a été publié dans
Nature Cardiovascular Research. 2024-06-01, vol. 3, n° 6, p. 619-621
Résumé en anglais
Rare and common variants in HTRA1 are associated with ischemic stroke. Research now sheds light on the underlying genetic architecture and suggests a vasculopathy with a broader phenotypic spectrum. Lower HTRA1 protease ...Lire la suite >
Rare and common variants in HTRA1 are associated with ischemic stroke. Research now sheds light on the underlying genetic architecture and suggests a vasculopathy with a broader phenotypic spectrum. Lower HTRA1 protease activity and circulating levels both predict an increased risk of ischemic stroke and coronary artery disease.< Réduire
Unités de recherche