Directing the Self-Assembly of Aromatic Foldamer Helices using Acridine Appendages and Metal Coordination
Language
EN
Article de revue
This item was published in
Chemistry – A European Journal. 2022-11-07, vol. 28, n° 62
English Abstract
Abstract Folded molecules provide complex interaction interfaces amenable to sophisticated self-assembly motifs. Because of their high conformational stability, aromatic foldamers constitute suitable candidates for the ...Read more >
Abstract Folded molecules provide complex interaction interfaces amenable to sophisticated self-assembly motifs. Because of their high conformational stability, aromatic foldamers constitute suitable candidates for the rational elaboration of self-assembled architectures. Several multiturn helical aromatic oligoamides have been synthesized that possess arrays of acridine appendages pointing in one or two directions. The acridine units were shown to direct self-assembly in the solid state via aromatic stacking leading to recurrent helix-helix association patterns under the form of discrete dimers or extended arrays. In the presence of Pd(II), metal coordination of the acridine units overwhelms other forces and generates new metal-mediated multihelical self-assemblies, including macrocycles. These observations demonstrate simple access to different types of foldamer-containing architectures, ranging from discrete objects to 1D and, by extension, 2D and 3D arrays.Read less <
English Keywords
Aromatic stacking
Foldamer
Helical conformation
Metal coordination
Self-assembly