This study investigated whether the visual recognition of neutral words might be influenced by the emotional dimensions (i.e., valence and arousal) of orthographically similar lexical representations, and whether this might also depend on emotional-related traits of participants (i.e., alexithymia). To this end, 108 participants performed a lexical decision task with 80 neutral words with a higher frequency orthographic neighbor that varied in valence (from neutral to negative) and arousal (from low to high). The main finding was the expected interaction effect between the valence and arousal of the neighbor on the lexical decision times of neutral stimulus words. Longer reaction times were found when the valence score of the neighbor decreased from neutral to negative for words with a low-arousal orthographic neighbor while this emotional neighbor effect was reversed for words with a high-arousal negative neighbor. This combined influence of the valence and arousal of the neighbor was interpreted in terms of increased lexical competition processes and direct influence of the affective system on the participant?s response. Moreover, this interaction effect was smaller when the level of alexithymia of the participants increased, suggesting that people with a higher level of alexithymia are less sensitive to the emotional content of the neighbor. The results are discussed within an interactive activation model of visual word recognition incorporating an affective system with valence and arousal dimensions, with regard to the role of the alexithymia level of participants.Read less <