Phosphatidylinositol-4-phosphate joins the dance of plant autophagosome formation
Language
EN
Article de revue
This item was published in
Autophagy. 2022-10-10p. 1-2
English Abstract
In plants, macroautophagy/autophagy is a key mechanism that contributes to their ability to cope with a wide range of environmental constraints such as drought, nutrient starvation or pathogen resistance. Nevertheless, the ...Read more >
In plants, macroautophagy/autophagy is a key mechanism that contributes to their ability to cope with a wide range of environmental constraints such as drought, nutrient starvation or pathogen resistance. Nevertheless, the molecular mechanisms of plant autophagy, and notably that of autophagosome formation, remain poorly understood. As the starting point of our recent paper, we considered the potential functional contribution of lipids in the numerous membrane-remodeling steps involved in this process. By combining biochemistry, genetics, cell biology and high-resolution 3D imaging, we unraveled the function of the lipid phosphatidylinositol-4-phosphate (PtdIns4P) in autophagy in thus providing novel insights into the assembly of autophagosomes in plant cells.Read less <
English Keywords
Arabidopsis
Autophagosomes
Environmental stresses
Lipids
Phosphatidylinositol-4-phosphate
Plasma membrane
European Project
European Union’s Horizon 2020 research and innovation programme