Phosphatidylinositol-4-phosphate joins the dance of plant autophagosome formation
Idioma
EN
Article de revue
Este ítem está publicado en
Autophagy. 2022-10-10p. 1-2
Resumen en inglés
In plants, macroautophagy/autophagy is a key mechanism that contributes to their ability to cope with a wide range of environmental constraints such as drought, nutrient starvation or pathogen resistance. Nevertheless, the ...Leer más >
In plants, macroautophagy/autophagy is a key mechanism that contributes to their ability to cope with a wide range of environmental constraints such as drought, nutrient starvation or pathogen resistance. Nevertheless, the molecular mechanisms of plant autophagy, and notably that of autophagosome formation, remain poorly understood. As the starting point of our recent paper, we considered the potential functional contribution of lipids in the numerous membrane-remodeling steps involved in this process. By combining biochemistry, genetics, cell biology and high-resolution 3D imaging, we unraveled the function of the lipid phosphatidylinositol-4-phosphate (PtdIns4P) in autophagy in thus providing novel insights into the assembly of autophagosomes in plant cells.< Leer menos
Palabras clave en inglés
Arabidopsis
Autophagosomes
Environmental stresses
Lipids
Phosphatidylinositol-4-phosphate
Plasma membrane
Proyecto europeo
European Union’s Horizon 2020 research and innovation programme
Centros de investigación