Phosphatidylinositol-4-phosphate joins the dance of plant autophagosome formation
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EN
Article de revue
Ce document a été publié dans
Autophagy. 2022-10-10p. 1-2
Résumé en anglais
In plants, macroautophagy/autophagy is a key mechanism that contributes to their ability to cope with a wide range of environmental constraints such as drought, nutrient starvation or pathogen resistance. Nevertheless, the ...Lire la suite >
In plants, macroautophagy/autophagy is a key mechanism that contributes to their ability to cope with a wide range of environmental constraints such as drought, nutrient starvation or pathogen resistance. Nevertheless, the molecular mechanisms of plant autophagy, and notably that of autophagosome formation, remain poorly understood. As the starting point of our recent paper, we considered the potential functional contribution of lipids in the numerous membrane-remodeling steps involved in this process. By combining biochemistry, genetics, cell biology and high-resolution 3D imaging, we unraveled the function of the lipid phosphatidylinositol-4-phosphate (PtdIns4P) in autophagy in thus providing novel insights into the assembly of autophagosomes in plant cells.< Réduire
Mots clés en anglais
Arabidopsis
Autophagosomes
Environmental stresses
Lipids
Phosphatidylinositol-4-phosphate
Plasma membrane
Projet Européen
European Union’s Horizon 2020 research and innovation programme
Unités de recherche