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Role of the AheABC efflux pump in Aeromonas hydrophila intrinsic multidrug resistance.
Language
EN
Article de revue
This item was published in
Antimicrobial Agents and Chemotherapy. 2008-04-01, vol. 52, n° 4, p. 1559-63
English Abstract
Gene inactivation and complementation experiments showed that the tripartite AheABC efflux pump of Aeromonas hydrophila extruded at least 13 substrates, including nine antibiotics. The use of phenylalanine-arginine-beta- ...Read more >
Gene inactivation and complementation experiments showed that the tripartite AheABC efflux pump of Aeromonas hydrophila extruded at least 13 substrates, including nine antibiotics. The use of phenylalanine-arginine-beta-naphthylamide (PAbetaN) revealed an additional system(s) contributing to intrinsic resistance. This is the first analysis of the role of multidrug efflux systems in Aeromonas spp.Read less <
English Keywords
Aeromonas hydrophila
Anti-Bacterial Agents
Bacterial Proteins
Biological Transport
Active
Dipeptides
Drug Resistance
Multiple
Bacterial
Humans
Microbial Sensitivity Tests
Molecular Sequence Data
Sequence Analysis
DNA
Substrate Specificity