Long genetic and social isolation in Neanderthals before their extinction
SEGUIN-ORLANDO, Andaine
Centre d'anthropologie et de génomique de Toulouse [CAGT]
Section for GeoGenetics
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Centre d'anthropologie et de génomique de Toulouse [CAGT]
Section for GeoGenetics
SEGUIN-ORLANDO, Andaine
Centre d'anthropologie et de génomique de Toulouse [CAGT]
Section for GeoGenetics
Centre d'anthropologie et de génomique de Toulouse [CAGT]
Section for GeoGenetics
METZ, Laure
Laboratoire méditerranéen de préhistoire Europe-Afrique [LAMPEA]
University of Connecticut [UCONN]
Laboratoire méditerranéen de préhistoire Europe-Afrique [LAMPEA]
University of Connecticut [UCONN]
DEVIESE, Thibaut
Centre Européen de Recherche et d'Enseignement des Géosciences de l'Environnement [CEREGE]
Centre Européen de Recherche et d'Enseignement des Géosciences de l'Environnement [CEREGE]
TENAILLEAU, Christophe
Centre interuniversitaire de recherche et d'ingénierie des matériaux [CIRIMAT]
< Reduce
Centre interuniversitaire de recherche et d'ingénierie des matériaux [CIRIMAT]
Language
en
Article de revue
This item was published in
Cell Genomics. 2024-09-11, vol. 4, n° 9, p. 100593
Elsevier
English Abstract
Neanderthal genomes have been recovered from sites across Eurasia, painting an increasingly complex picture of their populations' structure that mostly indicates that late European Neanderthals belonged to a single ...Read more >
Neanderthal genomes have been recovered from sites across Eurasia, painting an increasingly complex picture of their populations' structure that mostly indicates that late European Neanderthals belonged to a single metapopulation with no significant evidence of population structure. Here, we report the discovery of a late Neanderthal individual, nicknamed "Thorin," from Grotte Mandrin in Mediterranean France, and his genome. These dentognathic fossils, including a rare example of distomolars, are associated with a rich archeological record of Neanderthal final technological traditions in this region ∼50-42 thousand years ago. Thorin's genome reveals a relatively early divergence of ∼105 ka with other late Neanderthals. Thorin belonged to a population with a small group size that showed no genetic introgression with other known late European Neanderthals, revealing some 50 ka of genetic isolation of his lineage despite them living in neighboring regions. These results have important implications for resolving competing hypotheses about causes of the disappearance of the Neanderthals. >Read less <
English Keywords
Europe
Neanderthal extinction
fossils
genetic and social isolation
genetic divergence
genomics
last Neanderthals
population structure
proteomics
Origin
Hal importedCollections