Association between Dental Scores and Saliva Uremic Toxins
RIGOTHIER, Claire
Service de Néphrologie-transplantation-dialyse [Bordeaux]
Bioingénierie tissulaire [BIOTIS]
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Service de Néphrologie-transplantation-dialyse [Bordeaux]
Bioingénierie tissulaire [BIOTIS]
RIGOTHIER, Claire
Service de Néphrologie-transplantation-dialyse [Bordeaux]
Bioingénierie tissulaire [BIOTIS]
Service de Néphrologie-transplantation-dialyse [Bordeaux]
Bioingénierie tissulaire [BIOTIS]
COMBE, Christian
Service de Néphrologie-transplantation-dialyse [Bordeaux]
Bioingénierie tissulaire [BIOTIS]
Service de Néphrologie-transplantation-dialyse [Bordeaux]
Bioingénierie tissulaire [BIOTIS]
LARABI, Islam Amine
Infection et inflammation [2I]
Hôpital Raymond Poincaré (Garches) [GHU AP-HP Université Paris-Saclay]
Infection et inflammation [2I]
Hôpital Raymond Poincaré (Garches) [GHU AP-HP Université Paris-Saclay]
MASSY, Ziad
Centre de recherche en épidémiologie et santé des populations [CESP]
Service Néphrologie/Dialyse [AP-HP Ambroise-Paré]
Centre de recherche en épidémiologie et santé des populations [CESP]
Service Néphrologie/Dialyse [AP-HP Ambroise-Paré]
ALVAREZ, Jean Claude
Infection et inflammation [2I]
Hôpital Raymond Poincaré (Garches) [GHU AP-HP Université Paris-Saclay]
< Réduire
Infection et inflammation [2I]
Hôpital Raymond Poincaré (Garches) [GHU AP-HP Université Paris-Saclay]
Langue
EN
Article de revue
Ce document a été publié dans
Toxins. 2023, vol. 15, n° 11
Résumé en anglais
Dental health is frequently altered in patients with chronic kidney disease. We conducted a prospective study on dental health in CKD patients with a specific interest in the association between dental health issues and ...Lire la suite >
Dental health is frequently altered in patients with chronic kidney disease. We conducted a prospective study on dental health in CKD patients with a specific interest in the association between dental health issues and the accumulation of uremic toxins in the saliva. A total of 88 patients were included in the study, with chronic kidney disease stage 2 to 5 (without kidney replacement). We analysed the total concentrations of eight uremic toxins (trimethylamine N-oxide -TMAO-, Indoxyl Sulfate, P-cresyl-sulfate, Indole 3-acetic acid, 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid -CMPF-, Kynurenine, Hippuric acid and Phenylacetylglutamine) and three precursors of uremic toxins (Tyrosine, Phenylalanine and Tryptophan) in the saliva using LC-MS/MS. We observed, for the first time, the association between various dental scores: DMFT, FST, CPITN, and OHIS, and saliva uremic toxins and precursors: TMAO, indoxyl sulfate, or hippuric acid. Further prospective interventional studies are required to confirm our results.< Réduire
Mots clés en anglais
chronic kidney disease
dental health
saliva
uremic toxins