Mitochondrial energetic metabolism: a simplified model of TCA cycle with ATP production.
Langue
en
Article de revue
Ce document a été publié dans
Journal of Theoretical Biology. 2009-06-07, vol. 258, n° 3, p. 455-64
Elsevier
Résumé en anglais
Mitochondria play a central role in cellular energetic metabolism. The essential parts of this metabolism are the tricarboxylic acid (TCA) cycle, the respiratory chain and the adenosine triphosphate (ATP) synthesis machinery. ...Lire la suite >
Mitochondria play a central role in cellular energetic metabolism. The essential parts of this metabolism are the tricarboxylic acid (TCA) cycle, the respiratory chain and the adenosine triphosphate (ATP) synthesis machinery. Here a simplified model of these three metabolic components with a limited set of differential equations is presented. The existence of a steady state is demonstrated and results of numerical simulations are presented. The relevance of a simple model to represent actual in vivo behavior is discussed.< Réduire
Origine
Importé de halUnités de recherche