Mitochondrial energetic metabolism: a simplified model of TCA cycle with ATP production.
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en
Article de revue
Este ítem está publicado en
Journal of Theoretical Biology. 2009-06-07, vol. 258, n° 3, p. 455-64
Elsevier
Resumen en inglés
Mitochondria play a central role in cellular energetic metabolism. The essential parts of this metabolism are the tricarboxylic acid (TCA) cycle, the respiratory chain and the adenosine triphosphate (ATP) synthesis machinery. ...Leer más >
Mitochondria play a central role in cellular energetic metabolism. The essential parts of this metabolism are the tricarboxylic acid (TCA) cycle, the respiratory chain and the adenosine triphosphate (ATP) synthesis machinery. Here a simplified model of these three metabolic components with a limited set of differential equations is presented. The existence of a steady state is demonstrated and results of numerical simulations are presented. The relevance of a simple model to represent actual in vivo behavior is discussed.< Leer menos
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