scCVD diamond membrane based microdosimeter for hadron therapy
TROMSON, Dominique
Laboratoire Capteurs et Architectures Electroniques (CEA, LIST) [LCAE (CEA, LIST)]
Laboratoire Capteurs et Architectures Electroniques (CEA, LIST) [LCAE (CEA, LIST)]
POURCHER, Thierry
Transporteurs et Imagerie, Radiothérapie en Oncologie et Mécanismes biologiques des Altérations du Tissu Osseux [TIRO-MATOs UMR E4320]
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Transporteurs et Imagerie, Radiothérapie en Oncologie et Mécanismes biologiques des Altérations du Tissu Osseux [TIRO-MATOs UMR E4320]
Language
en
Article de revue
This item was published in
physica status solidi (a). 2018-11, vol. 215, n° 22, p. 1800383
Wiley
English Abstract
Hadron therapy is an innovative mode of radiotherapy (RT) for cancer treatment which enables tumor cells to be more effectively destroyed than conventional RT using photons. The precise knowledge of the lineal energy of ...Read more >
Hadron therapy is an innovative mode of radiotherapy (RT) for cancer treatment which enables tumor cells to be more effectively destroyed than conventional RT using photons. The precise knowledge of the lineal energy of particles is used in the field of microdosimetry (MKM model) as a fundamental parameter in the prediction of the relative biological efficiency (RBE) of clinical beams. Based on single-crystal CVD (scCVD) super-thin diamond membranes obtained using deep Ar/O$_2$ plasma etching, prototypes of solid-state microdosimeters for lineal energy measurements are produced at the Diamond Sensors Laboratory of CEA-LIST. The response of a diamond membrane microdosimeter to single projectiles is investigated in ion microbeams. The microdosimeter is irradiated using a raster scanning method and the charge transport properties of the device are determined with sub-micron precision by measuring the charge collection efficiency (CCE), the μSVs 3D spatial definition and the pulse-height spectra. A prototype of this novel microdosimeter is then tested in a 100 MeV therapeutic proton beam at the Institute Curie − Proton Therapy Centre in Orsay. All results effectively demonstrate the great potential for this device to be used for studies of the RBE in clinical applications.Read less <
English Keywords
radiotherapy
ionizing radiation
radioactivity
cancer
tumor
dosimetry
microdosimetry
diamond
Chemical Vapor Deposition (CVD)
thin film
sensor
protons
instrumentation
nuclear instrumentation
diamond microdosimeter
hadron therapy
ion beam induced charge
lineal energy
micro-sensitive volumes
European Project
Advanced European Infrastructures for Detectors at Accelerators
Origin
Hal imported