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hal.structure.identifierLaboratoire Capteurs Diamant (CEA, LIST) [LCD (CEA, LIST)]
dc.contributor.authorZAHRADNIK, Izabella
hal.structure.identifierLaboratoire Capteurs Diamant (CEA, LIST) [LCD (CEA, LIST)]
dc.contributor.authorPOMORSKI, Michal
hal.structure.identifierInstitut Curie Centre de Protonthérapie d'Orsay
dc.contributor.authorDE MARZI, Ludovic
hal.structure.identifierLaboratoire Capteurs et Architectures Electroniques (CEA, LIST) [LCAE (CEA, LIST)]
dc.contributor.authorTROMSON, Dominique
hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorBARBERET, Philippe
hal.structure.identifierInstitut Ruđer Bošković [IRB]
dc.contributor.authorSKUKAN, Natko
hal.structure.identifierLaboratoire Capteurs Diamant (CEA, LIST) [LCD (CEA, LIST)]
dc.contributor.authorBERGONZO, Philippe
hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorDEVÈS, Guillaume
hal.structure.identifierCentre de Lutte contre le Cancer Antoine Lacassagne [Nice] [UNICANCER/CAL]
dc.contributor.authorHERAULT, Joël
hal.structure.identifierGunma University
dc.contributor.authorKADA, Wataru
hal.structure.identifierTransporteurs et Imagerie, Radiothérapie en Oncologie et Mécanismes biologiques des Altérations du Tissu Osseux [TIRO-MATOs UMR E4320]
dc.contributor.authorPOURCHER, Thierry
hal.structure.identifierLaboratoire Capteurs Diamant (CEA, LIST) [LCD (CEA, LIST)]
dc.contributor.authorSAADA, Samuel
dc.date.accessioned2023-11-20T16:39:27Z
dc.date.available2023-11-20T16:39:27Z
dc.date.issued2018-11
dc.identifier.issn0031-8965
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/184956
dc.description.abstractEnHadron therapy is an innovative mode of radiotherapy (RT) for cancer treatment which enables tumor cells to be more effectively destroyed than conventional RT using photons. The precise knowledge of the lineal energy of particles is used in the field of microdosimetry (MKM model) as a fundamental parameter in the prediction of the relative biological efficiency (RBE) of clinical beams. Based on single-crystal CVD (scCVD) super-thin diamond membranes obtained using deep Ar/O$_2$ plasma etching, prototypes of solid-state microdosimeters for lineal energy measurements are produced at the Diamond Sensors Laboratory of CEA-LIST. The response of a diamond membrane microdosimeter to single projectiles is investigated in ion microbeams. The microdosimeter is irradiated using a raster scanning method and the charge transport properties of the device are determined with sub-micron precision by measuring the charge collection efficiency (CCE), the μSVs 3D spatial definition and the pulse-height spectra. A prototype of this novel microdosimeter is then tested in a 100 MeV therapeutic proton beam at the Institute Curie − Proton Therapy Centre in Orsay. All results effectively demonstrate the great potential for this device to be used for studies of the RBE in clinical applications.
dc.language.isoen
dc.publisherWiley
dc.subject.enradiotherapy
dc.subject.enionizing radiation
dc.subject.enradioactivity
dc.subject.encancer
dc.subject.entumor
dc.subject.endosimetry
dc.subject.enmicrodosimetry
dc.subject.endiamond
dc.subject.enChemical Vapor Deposition (CVD)
dc.subject.enthin film
dc.subject.ensensor
dc.subject.enprotons
dc.subject.eninstrumentation
dc.subject.ennuclear instrumentation
dc.subject.endiamond microdosimeter
dc.subject.enhadron therapy
dc.subject.enion beam induced charge
dc.subject.enlineal energy
dc.subject.enmicro-sensitive volumes
dc.title.enscCVD diamond membrane based microdosimeter for hadron therapy
dc.typeArticle de revue
dc.identifier.doi10.1002/pssa.201800383
dc.subject.halPhysique [physics]/Physique [physics]/Physique Médicale [physics.med-ph]
dc.description.sponsorshipEuropeAdvanced European Infrastructures for Detectors at Accelerators
bordeaux.journalphysica status solidi (a)
bordeaux.page1800383
bordeaux.volume215
bordeaux.hal.laboratoriesCentre d'Études Nucléaires de Bordeaux Gradignan (CENBG)*
bordeaux.issue22
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifiercea-04146874
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//cea-04146874v1
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