Neuromodulation in developing motor microcircuits.
Language
EN
Article de revue
This item was published in
Current Opinion in Neurobiology. 2014-12-01, vol. 29, p. 73-81
English Abstract
Neuromodulation confers operational flexibility on motor network output and resulting behaviour. Furthermore, neuromodulators play crucial long-term roles in the assembly and maturational shaping of the same networks as ...Read more >
Neuromodulation confers operational flexibility on motor network output and resulting behaviour. Furthermore, neuromodulators play crucial long-term roles in the assembly and maturational shaping of the same networks as they develop. Although previous studies have identified such modulator-dependent contributions to microcircuit ontogeny, some of the underlying mechanisms are only now being elucidated. Deciphering the role of neuromodulatory systems in motor network development has potentially important implications for post-lesional regenerative strategies in adults.Read less <
English Keywords
Animals
Biological Evolution
Efferent Pathways
Humans
Motor Neurons
Nerve Net
Neurotransmitter Agents