Neuromodulation in developing motor microcircuits.
Idioma
EN
Article de revue
Este ítem está publicado en
Current Opinion in Neurobiology. 2014-12-01, vol. 29, p. 73-81
Resumen en inglés
Neuromodulation confers operational flexibility on motor network output and resulting behaviour. Furthermore, neuromodulators play crucial long-term roles in the assembly and maturational shaping of the same networks as ...Leer más >
Neuromodulation confers operational flexibility on motor network output and resulting behaviour. Furthermore, neuromodulators play crucial long-term roles in the assembly and maturational shaping of the same networks as they develop. Although previous studies have identified such modulator-dependent contributions to microcircuit ontogeny, some of the underlying mechanisms are only now being elucidated. Deciphering the role of neuromodulatory systems in motor network development has potentially important implications for post-lesional regenerative strategies in adults.< Leer menos
Palabras clave en inglés
Animals
Biological Evolution
Efferent Pathways
Humans
Motor Neurons
Nerve Net
Neurotransmitter Agents
Centros de investigación