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dc.rights.licenseopenen_US
hal.structure.identifierBordeaux Research In Translational Oncology [Bordeaux] [BaRITOn]
dc.contributor.authorALBARET, Guillaume
hal.structure.identifierBordeaux Research In Translational Oncology [Bordeaux] [BaRITOn]
dc.contributor.authorSIFRE, Elodie
hal.structure.identifierBordeaux Research In Translational Oncology [Bordeaux] [BaRITOn]
dc.contributor.authorFLOCH, Pauline
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorLAYE, Sophie
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorAUBERT, Agnes
hal.structure.identifierBordeaux Research In Translational Oncology [Bordeaux] [BaRITOn]
dc.contributor.authorDUBUS, Pierre
hal.structure.identifierBordeaux Research In Translational Oncology [Bordeaux] [BaRITOn]
dc.contributor.authorAZZI-MARTIN, Lamia
hal.structure.identifierBordeaux Research In Translational Oncology [Bordeaux] [BaRITOn]
dc.contributor.authorGIESE, Alban
hal.structure.identifierBordeaux Research In Translational Oncology [Bordeaux] [BaRITOn]
dc.contributor.authorSALLES, Nathalie
hal.structure.identifierBordeaux Research In Translational Oncology [Bordeaux] [BaRITOn]
dc.contributor.authorMEGRAUD, Francis
hal.structure.identifierBordeaux Research In Translational Oncology [Bordeaux] [BaRITOn]
dc.contributor.authorVARON, Christine
hal.structure.identifierBordeaux Research In Translational Oncology [Bordeaux] [BaRITOn]
dc.contributor.authorLEHOURS, Philippe
hal.structure.identifierBordeaux Research In Translational Oncology [Bordeaux] [BaRITOn]
dc.contributor.authorROUBAUD-BAUDRON, Claire
dc.date.accessioned2021-09-22T12:10:02Z
dc.date.available2021-09-22T12:10:02Z
dc.date.issued2020
dc.identifier.issn1387-2877 (Print) 1875-8908 (Online)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/112323
dc.description.abstractEnDespite extensive research, the origin of Alzheimer's disease (AD) remains unknown. The role of infectious pathogens has recently emerged. Epidemiological studies have shown that Helicobacter pylori infection increases the risk of developing AD. We hypothesized that H. pylon-induced gastritis may be associated with a systemic inflammation and finally neuroinflammation. C57BL/6 mice were infected with H. pylori (n= 15) or Helicobacter felis (n= 13) or left uninfected (n = 9) during 18 months. Gastritis, amyloid deposition, astroglial and microglial cell area, and systemic and brain cytokines were assessed. The infection (H. felis>H. pylori) induced a severe gastritis and an increased neuroinflammation but without brain amyloid deposition or systemic inflammation.
dc.language.isoENen_US
dc.subject.enAlzheimer's disease
dc.subject.endementia
dc.subject.engastric inflammation
dc.subject.enGFAP
dc.subject.enHelicobacter infection
dc.subject.eniba-1
dc.subject.enneuroinflammation
dc.title.enAlzheimer's disease and Helicobacter pylori infection: inflammation from stomach to brain?
dc.typeArticle de revueen_US
dc.identifier.doi10.3233/JAD-190496en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed31868664en_US
bordeaux.journalJournal of Alzheimer's Diseaseen_US
bordeaux.page801-809en_US
bordeaux.volume73en_US
bordeaux.hal.laboratoriesNutriNeurO (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286en_US
bordeaux.issue2en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINRAEen_US
bordeaux.teamPsychoneuroimmunologie et Nutrition: Approches expérimentales et cliniquesen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20Alzheimer's%20Disease&rft.date=2020&rft.volume=73&rft.issue=2&rft.spage=801-809&rft.epage=801-809&rft.eissn=1387-2877%20(Print)%201875-8908%20(Online)&rft.issn=1387-2877%20(Print)%201875-8908%20(Online)&rft.au=ALBARET,%20Guillaume&SIFRE,%20Elodie&FLOCH,%20Pauline&LAYE,%20Sophie&AUBERT,%20Agnes&rft.genre=article


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