In situ iodination and X-ray crystal structure of a foldamer helix bundle
Langue
en
Article de revue
Ce document a été publié dans
Chemical Communications. 2016, vol. 52, n° 6, p. 1202-1205
Résumé en anglais
We report here the efficient in situ iodination of tyrosine-type side-chains located within a foldamer helix bundle, permitting structure determination using single-wavelength anomalous diffraction (SAD) methods. We suggest ...Lire la suite >
We report here the efficient in situ iodination of tyrosine-type side-chains located within a foldamer helix bundle, permitting structure determination using single-wavelength anomalous diffraction (SAD) methods. We suggest that this simple method may be of use to those engaged in structural foldamer research as a potential solution to the phase problem.< Réduire
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