In situ iodination and X-ray crystal structure of a foldamer helix bundle
Idioma
en
Article de revue
Este ítem está publicado en
Chemical Communications. 2016, vol. 52, n° 6, p. 1202-1205
Resumen en inglés
We report here the efficient in situ iodination of tyrosine-type side-chains located within a foldamer helix bundle, permitting structure determination using single-wavelength anomalous diffraction (SAD) methods. We suggest ...Leer más >
We report here the efficient in situ iodination of tyrosine-type side-chains located within a foldamer helix bundle, permitting structure determination using single-wavelength anomalous diffraction (SAD) methods. We suggest that this simple method may be of use to those engaged in structural foldamer research as a potential solution to the phase problem.< Leer menos
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