Multivalent Interactions between an Aromatic Helical Foldamer and a DNA G-Quadruplex in the Solid State
Langue
en
Article de revue
Ce document a été publié dans
ChemBioChem. 2016, vol. 17, n° 20, p. 1911-1914
Résumé en anglais
Quinoline-based oligoamide foldamers have been identified as a potent class of ligands for G-quadruplex DNA. Their helical structure is thought to target G-quadruplex loops or grooves and not G-tetrads. We report a co-crystal ...Lire la suite >