The amount of H2 present in spiral galaxies remains uncertain, particularly in the dim outer regions and in low-metallicity environments. We present high-resolution CO(1-0) observations with the Plateau de Bure interferometer of the most distant molecular cloud in the local group galaxy M 33. The cloud is a single entity rather than a set of smaller clouds within the broad beam of the original single-dish observations. The interferometer and single-dish fluxes are very similar and the line widths are indistinguishable, despite the difference in beamsize. At a spatial resolution of 10 pc, beyond the optical radius of the M 33, the CO brightness temperature reaches 2.4 Kelvins. A virial mass estimate for the cloud yields a mass of 4.3 × 104 M&sun; and a ratio N(H2)/ICO(1-0) ≃ 3.5 × 1020 cm-2/(K km s-1). While no velocity gradient is seen where the emission is strong, the velocity is redshifted to the extreme SW and blue-shifted to the far NE. If the orientation of the cloud is along the plane of the disk (i.e. not perpendicular), then these velocities correspond to slow infall or accretion. The rather modest infall rate would be about 2 × 10-4 M&sun; yr-1. Based on observations carried out with the IRAM Plateau de Bure Interferometer. IRAM is supported by INSU/CNRS (France), MPG (Germany) and IGN (Spain).Data cube in FITS files is only available at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/548/A52< Réduire