Analysis of recent detections of water by Herschel/HIFI-PACS and Cassini/CIRS suggest for a steep gradient of the water profile in the lower stratosphere of Titan's atmosphere (Cottini, V., Nixon, C.A., Jennings, D.E., Anderson, C.M., Gorius, N., Bjoraker, G.L., Coustenis, A., Teanby, N.A., Achterberg, R.K., Béezard, B., de Kok, R., Lellouch, E., Irwin, P.G.J., Flasar, F.M., Bampasidis, G. [2012]. Icarus 220, 855-862; Moreno, R., Lellouch, E., Lara, L.M., Feuchtgruber, H., Rengel, M., Hartogh, P., Courtin, R. [2012]. Icarus 221, 753-767). This result provides a good opportunity to better understand the origin of oxygen compounds. However, the current photochemical models use an incomplete oxygen chemical scheme. In the present work, we improve the photochemistry of oxygen and introduce in particular a coupling between hydrocarbon, oxygen and nitrogen chemistries. Through the use of several different scenarios, we show that some oxygen compound abundances are sensitive to the nature of oxygen atoms (O+, OH and H2O) and the source of the flux (micrometeorites ablation or Enceladus' plume activity). Our model also predicts the presence of new and as yet undetected compounds such as NO (nitric oxide), HNO (nitrosyl hydride), HNCO (isocyanic acid) and N2O (nitrous oxide). Their future putative detection will give valuable constraints to discriminate between the different hypotheses for the nature and the source of oxygen compounds in the atmosphere of Titan. Through the use of a Monte Carlo-based uncertainty propagation study and global sensitivity analysis, we identify the key reactions that should be studied in priority to improve coupled photochemical models of Titan's atmosphere.< Réduire