High and low CO2 partial pressure (Pco2) levels can induce consequences to the internal system of a karstic cave. This then can further affect the state of the cave. Subsequently, speleothem growths and the walls with prehistorical paintings and engravings will be affected with either calcite dissolution or precipitation. Thus, pinpointing the major components of Pco2 is found indispensable. In this paper, a method is proposed in order to (1) identify the major components of the Pco2 and (2) quantify each specific contribution to the Pco2. Pco2, air temperature, air pressure, and water flow were measured from 2008 to 2010 in Lascaux Cave (Southwest of France). Pco2 varied from 0.62% (6200 ppm) in summer to 0.04% (400 ppm) in winter. We identified three major components: (1) seasonal: component A; (2) low frequency: component B; and (3) high frequency: component C. The method is applied to estimate the contribution of each component. Component A was modelled with a sinusoid curve fitted to the Pco2 measures. This component was subtracted from the measured Pco2. Then, from the remaining value of Pco2, Fourier transform, frequency filtering, and inverse Fourier transform were applied to separate high- and low-frequency components. As a result, the seasonal component A contributes 77% of the measured Pco2, while components B and C supply 13 and 11%, respectively. The three identified components have links with environmental parameters such as temperature, water flow, and atmospheric pressure. Hypotheses were proposed to describe these links. Knowledge on these aspects can help in cave management and protection specifically in answering the question: which parameter should be given more attention.< Réduire