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Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae.
| dc.rights.license | open | en_US |
| hal.structure.identifier | Microbiologie Fondamentale et Pathogénicité [MFP] | |
| dc.contributor.author | DUBOIS, Véronique | |
| dc.contributor.author | POIREL, Laurent | |
| dc.contributor.author | DEMARTHE, François | |
| dc.contributor.author | ARPIN, Corinne
IDREF: 093324626 | |
| dc.contributor.author | COULANGE, Laure | |
| dc.contributor.author | MINARINI, Luciene A R | |
| dc.contributor.author | BEZIAN, Marie-Christine | |
| dc.contributor.author | NORDMANN, Patrice | |
| dc.contributor.author | QUENTIN, Claudine | |
| dc.date.accessioned | 2024-10-30T14:38:19Z | |
| dc.date.available | 2024-10-30T14:38:19Z | |
| dc.date.issued | 2008-10-01 | |
| dc.identifier.issn | 1098-6596 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/203002 | |
| dc.description.abstractEn | A clinical strain of Klebsiella pneumoniae was found to possess the chromosomal gene bla(SHV-56), encoding a new inhibitor-resistant beta-lactamase with a pI of 7.6. SHV-56 is derived from SHV-11 by the single substitution K234R. This mutation therefore evidences a new critical site for inhibitor resistance among SHV enzymes. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | Aged | |
| dc.subject.en | Amino Acid Substitution | |
| dc.subject.en | Base Sequence | |
| dc.subject.en | DNA Primers | |
| dc.subject.en | DNA | |
| dc.subject.en | Bacterial | |
| dc.subject.en | Female | |
| dc.subject.en | Genes | |
| dc.subject.en | Bacterial | |
| dc.subject.en | Humans | |
| dc.subject.en | Isoelectric Point | |
| dc.subject.en | Kinetics | |
| dc.subject.en | Klebsiella Infections | |
| dc.subject.en | Klebsiella pneumoniae | |
| dc.subject.en | Molecular Sequence Data | |
| dc.subject.en | Mutagenesis | |
| dc.subject.en | Insertional | |
| dc.subject.en | Recombinant Proteins | |
| dc.subject.en | beta-Lactam Resistance | |
| dc.subject.en | beta-Lactamases | |
| dc.title.en | Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae. | |
| dc.title.alternative | Antimicrob Agents Chemother | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1128/AAC.00387-08 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Microbiologie et Parasitologie | en_US |
| dc.identifier.pubmed | 18663019 | en_US |
| bordeaux.journal | Antimicrobial Agents and Chemotherapy | en_US |
| bordeaux.page | 3792-4 | en_US |
| bordeaux.volume | 52 | en_US |
| bordeaux.hal.laboratories | MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234 | en_US |
| bordeaux.issue | 10 | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | pubmed | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | false | |
| workflow.import.source | pubmed | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Antimicrobial%20Agents%20and%20Chemotherapy&rft.date=2008-10-01&rft.volume=52&rft.issue=10&rft.spage=3792-4&rft.epage=3792-4&rft.eissn=1098-6596&rft.issn=1098-6596&rft.au=DUBOIS,%20V%C3%A9ronique&POIREL,%20Laurent&DEMARTHE,%20Fran%C3%A7ois&ARPIN,%20Corinne&COULANGE,%20Laure&rft.genre=article |
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