DUQUENNE, Pauline; SAMIERI, Cecilia; CHAMBARON, Stéphanie; BRINDISI, Marie-Claude; KESSE-GUYOT, Emmanuelle; GALAN, Pilar; HERCBERG, Serge; TOUVIER, Mathilde; LÉGER, Damien; FEZEU, Léopold; ANDREEVA, Valentina

doi:10.1038/s41598-024-62675-y

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DUQUENNE, Pauline
Nutritional Epidemiology Research Team | Equipe de Recherche en Epidémiologie Nutritionnelle [EREN [CRESS - U1153 / UMR_A 1125]]

SAMIERI, Cecilia

Bordeaux population health [BPH]

CHAMBARON, Stéphanie
Centre des Sciences du Goût et de l'Alimentation [Dijon] [CSGA]

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Article de revue

Ce document a été publié dans

Scientific Reports. 2024-05-24, vol. 14, n° 1, p. 11927

Résumé en anglais

The main objective of this study was to evaluate the association of the insomnia-anxiety comorbidity with incident type 2 diabetes (T2D) in a large prospective cohort. We selected adults without diabetes at baseline from the French NutriNet-Santé cohort who had completed the trait anxiety subscale of the Spielberger State-Trait Anxiety Inventory (STAI-T, 2013–2016) and a sleep questionnaire (2014); insomnia was defined according to established criteria. Using multivariable Cox models, we compared T2D risk across 4 groups: no insomnia or anxiety (reference), insomnia alone, anxiety alone (STAI-T ≥ 40), and comorbid anxiety and insomnia. Among 35,014 participants (mean baseline age: 52.4 ± 14.0 years; 76% women), 378 (1.1%) developed T2D over a mean follow-up of 5.9 ± 2.1 years. Overall, 28.5% of the sample had anxiety alone, 7.5%—insomnia alone, and 12.5%—both disorders. In the fully-adjusted model, a higher T2D risk was associated with anxiety-insomnia comorbidity (HR = 1.40; 95% CI 1.01, 1.94), but not with each disorder separately, compared to the group without insomnia or anxiety. The findings supported a positive association between anxiety-insomnia comorbidity and incident T2D among general-population adults. Future research using clinical diagnoses of mental disorders could confirm the findings and guide diabetes prevention programs.< Réduire

Mots clés en anglais

Comorbidity

Diabetes mellitus

Insomnia

Mental health

Prospective study

Anxiety Comorbidity Diabetes mellitus Insomnia Mental health Prospective study

Anxiety

URI

https://oskar-bordeaux.fr/handle/20.500.12278/201703

DOI

http://dx.doi.org/10.1038/s41598-024-62675-y

Project ANR

La santé mentale en tant que déterminant des maladies chroniques liées à la nutrition

Unités de recherche

Bordeaux Population Health Research Center (BPH) - UMR 1219