DAO, Tuyen; FERNANDES, Fabio; FAUQUIGNON, Martin; IBARBOURE, Emmanuel; PRIETO, Manuel; LE MEINS, Jean-Francois

doi:10.1039/C8SM00547H

Métadonnées

Licence d’utilisation du document

DAO, Tuyen
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Instituto Superior Técnico

FERNANDES, Fabio
Instituto Superior Técnico

FAUQUIGNON, Martin
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences

Langue

Article de revue

Ce document a été publié dans

Soft Matter. 2018, vol. 14, n° 31, p. 6476-6484

Royal Society of Chemistry

Résumé en anglais

In this work, the elasticity under stretching as well as fluidity of Giant Hybrid Unilamellar Vesicles (GHUV) has been studied. The membrane structuration of these GHUVs has been already studied at micro and nanoscale in a previous study of the team1. These GHUVs were obtained by the association of fluid phospholipid (POPC) and triblock copolymer poly(ethyleneoxide)-b-poly(dimethylsiloxane)-b-poly(ethyleneoxide). Although triblock copolymers’ architecture can facilitate vesicle formation , they have been scarcely used to generate GHUVs. We show, through micropipette aspiration and FRAP experiments, that the incorporation of a low amount of lipids in the polymer membrane leads to a significant loss of the toughness of the vesicle and subtle modification of lateral diffusion of polymer chains. We discuss the results within the framework of conformation of the triblock copolymer chain in the membrane, and of the presence of lipid nanodomains.< Réduire

Mots clés en anglais

Micropipette aspiration

Membrane properties

Hybrid vesicles

URI

https://oskar-bordeaux.fr/handle/20.500.12278/19960

DOI

http://dx.doi.org/10.1039/C8SM00547H

Projet Européen

Erasmus Mundus - International Doctoral School in Functional Materials

Origine

Importé de hal

Unités de recherche

Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629