The combination of block copolymers and phospholipids to form Giant Hybrid Unilamellar Vesicles (GHUVs) does not systematically lead to “intermediate” membrane properties.
DAO, Tuyen
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Instituto Superior Técnico
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Instituto Superior Técnico
FAUQUIGNON, Martin
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
See more >
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
DAO, Tuyen
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Instituto Superior Técnico
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Instituto Superior Técnico
FAUQUIGNON, Martin
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
IBARBOURE, Emmanuel
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
LE MEINS, Jean-Francois
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
< Reduce
Laboratoire de Chimie des Polymères Organiques [LCPO]
Team 3 LCPO : Polymer Self-Assembly & Life Sciences
Language
en
Article de revue
This item was published in
Soft Matter. 2018, vol. 14, n° 31, p. 6476-6484
Royal Society of Chemistry
English Abstract
In this work, the elasticity under stretching as well as fluidity of Giant Hybrid Unilamellar Vesicles (GHUV) has been studied. The membrane structuration of these GHUVs has been already studied at micro and nanoscale in ...Read more >
In this work, the elasticity under stretching as well as fluidity of Giant Hybrid Unilamellar Vesicles (GHUV) has been studied. The membrane structuration of these GHUVs has been already studied at micro and nanoscale in a previous study of the team1. These GHUVs were obtained by the association of fluid phospholipid (POPC) and triblock copolymer poly(ethyleneoxide)-b-poly(dimethylsiloxane)-b-poly(ethyleneoxide). Although triblock copolymers’ architecture can facilitate vesicle formation , they have been scarcely used to generate GHUVs. We show, through micropipette aspiration and FRAP experiments, that the incorporation of a low amount of lipids in the polymer membrane leads to a significant loss of the toughness of the vesicle and subtle modification of lateral diffusion of polymer chains. We discuss the results within the framework of conformation of the triblock copolymer chain in the membrane, and of the presence of lipid nanodomains.Read less <
English Keywords
Micropipette aspiration
Membrane properties
Hybrid vesicles
European Project
Erasmus Mundus - International Doctoral School in Functional Materials
Origin
Hal imported