Comparative genomics of protoploid Saccharomycetaceae
SHERMAN, David James
Models and Algorithms for the Genome [ MAGNOME]
Laboratoire Bordelais de Recherche en Informatique [LaBRI]
Models and Algorithms for the Genome [ MAGNOME]
Laboratoire Bordelais de Recherche en Informatique [LaBRI]
WEISSENBACH, Jean
Structure et évolution des génomes - UMR 8030 [SEG]
Genoscope - Centre national de séquençage [Evry] [GENOSCOPE]
Structure et évolution des génomes - UMR 8030 [SEG]
Genoscope - Centre national de séquençage [Evry] [GENOSCOPE]
WINCKER, Patrick
Genoscope - Centre national de séquençage [Evry] [GENOSCOPE]
Institut de Génomique d'Evry [IG]
Genoscope - Centre national de séquençage [Evry] [GENOSCOPE]
Institut de Génomique d'Evry [IG]
BARBE, Valerie
Structure et évolution des génomes - UMR 8030 [SEG]
Genoscope - Centre national de séquençage [Evry] [GENOSCOPE]
Structure et évolution des génomes - UMR 8030 [SEG]
Genoscope - Centre national de séquençage [Evry] [GENOSCOPE]
ANTHOUARD, Véronique
Structure et évolution des génomes - UMR 8030 [SEG]
Genoscope - Centre national de séquençage [Evry] [GENOSCOPE]
Structure et évolution des génomes - UMR 8030 [SEG]
Genoscope - Centre national de séquençage [Evry] [GENOSCOPE]
DURRENS, Pascal
Models and Algorithms for the Genome [ MAGNOME]
Laboratoire Bordelais de Recherche en Informatique [LaBRI]
Models and Algorithms for the Genome [ MAGNOME]
Laboratoire Bordelais de Recherche en Informatique [LaBRI]
MARTIN, Tiphaine
Models and Algorithms for the Genome [ MAGNOME]
Modèles et algorithmes pour la Bioinformatique et la Visualisation d'informations; [MABIOVIS]
Models and Algorithms for the Genome [ MAGNOME]
Modèles et algorithmes pour la Bioinformatique et la Visualisation d'informations; [MABIOVIS]
NIKOLSKI, Macha
Models and Algorithms for the Genome [ MAGNOME]
Laboratoire Bordelais de Recherche en Informatique [LaBRI]
Models and Algorithms for the Genome [ MAGNOME]
Laboratoire Bordelais de Recherche en Informatique [LaBRI]
GOEFFON, Adrien
Models and Algorithms for the Genome [ MAGNOME]
Laboratoire Bordelais de Recherche en Informatique [LaBRI]
Models and Algorithms for the Genome [ MAGNOME]
Laboratoire Bordelais de Recherche en Informatique [LaBRI]
PRIBYLOVA, Lenka
Génétique moléculaire, génomique, microbiologie [GMGM]
Department of Membrane Transport [Prague]
< Réduire
Génétique moléculaire, génomique, microbiologie [GMGM]
Department of Membrane Transport [Prague]
Langue
en
Article de revue
Ce document a été publié dans
Genome Research. 2009, vol. 19, p. 1696-1709
Cold Spring Harbor Laboratory Press
Résumé en anglais
Our knowledge on yeast genomes remains largely dominated by the extensive studies on Saccharomyces cerevisiae and the consequences of its ancestral duplication, leaving the evolution of the entire class of hemiascomycetes ...Lire la suite >
Our knowledge on yeast genomes remains largely dominated by the extensive studies on Saccharomyces cerevisiae and the consequences of its ancestral duplication, leaving the evolution of the entire class of hemiascomycetes only partly explored. We concentrate here on five species of Saccharomycetaceae, a large subdivision of hemiascomycetes, that we call "protoploid" because they diverged from the S. cerevisiae lineage prior to its genome duplication. We determined the complete genome sequences of three of these species, Kluyveromyces (Lachancea) thermotolerans and Saccharomyces (Lachancea) kluyveri (two members of the newly described Lachancea clade) and Zygosaccharomyces rouxii. We included in our comparisons the previously available sequences of Klyveromyces lactis and Ashbya (Eremothecium) gossypii. Despite their broad evolutionary range and significant individual variations in each lineage, the five protoploid Saccharomycetaceae share a core repertoire of ca. 3,300 protein families and a high degree of conserved synteny. Synteny blocks were used to define gene orthology and to infer ancestors. Far from representing minimal genomes without redundancy, the five protoploid yeasts contain numerous copies of paralogous genes, either dispersed or in tandem arrays, that, altogether, constitute a third of each genome. Ancient, conserved paralogs as well as novel, lineage-specific paralogs were identified.< Réduire
Project ANR
How do genes arise ? Lessons and questions from the evolution of yeast genomes.
Origine
Importé de halUnités de recherche