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dc.rights.licenseopenen_US
dc.contributor.authorGOMEZ-ZORITA, Saioa
dc.contributor.authorMILTON-LASKIBAR, Iñaki
dc.contributor.authorESEBERRI, Itziar
hal.structure.identifierUnité de Recherche Œnologie [Villenave d'Ornon] [OENO]
dc.contributor.authorBEAUMONT, Pauline
hal.structure.identifierUnité de Recherche Œnologie [Villenave d'Ornon] [OENO]
dc.contributor.authorCOURTOIS, Arnaud
IDREF: 092021301
hal.structure.identifierUnité de Recherche Œnologie [Villenave d'Ornon] [OENO]
dc.contributor.authorKRISA, Stéphanie
dc.contributor.authorPORTILLO, María P
dc.date.accessioned2024-04-11T13:49:22Z
dc.date.available2024-04-11T13:49:22Z
dc.date.issued2023-02-12
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/197568
dc.description.abstractEnViniferin is a phenolic compound belonging to the group of stilbenoids. In particular, ε-viniferin is a dimer of resveratrol, found in many plant genders, among which grapes (Vitis vinifera) are a primary source. Due to the fact that ε-viniferin is mainly present in the woody parts of plants, their use as a source of this bioactive compound is a very interesting issue in a circular economy. Both, in vitro studies carried out in pre-adipocytes and mature adipocytes and in vivo studies addressed in mice show that ε-viniferin is able to reduce fat accumulation. Moreover, it prevents the development of some obesity co-morbidities, such as type 2 diabetes, dyslipidemias, hypertension and fatty liver. ε-viniferin can be absorbed orally, but it shows a very low bioavailability. In this scenario, further research on animal models is needed to confirm the effects reported in a great number of studies; to determine which metabolites are involved, including the main one responsible for the biological effects observed and the mechanisms that justify these effects. In a further phase, human studies should be addressed in order to use ε-viniferin as a new tool for obesity management, as a nutraceutical or to be included in functional foods. © 2023 by the authors.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enviniferin
dc.subject.enobesity
dc.subject.englucose homeostasis
dc.subject.endyslipidemia
dc.subject.enfatty liver
dc.subject.enhypertension
dc.title.enBeneficial Effects of ϵ-Viniferin on Obesity and Related Health Alterations
dc.typeArticle de revueen_US
dc.identifier.doi10.3390/nu15040928en_US
dc.subject.halSciences du Vivant [q-bio]/Biologie végétaleen_US
bordeaux.journalNutrientsen_US
bordeaux.page928en_US
bordeaux.volume15en_US
bordeaux.hal.laboratoriesOenologie - UMR 1366en_US
bordeaux.issue4en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionBordeaux INPen_US
bordeaux.institutionINRAEen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
dc.rights.ccCC BYen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nutrients&rft.date=2023-02-12&rft.volume=15&rft.issue=4&rft.spage=928&rft.epage=928&rft.au=GOMEZ-ZORITA,%20Saioa&MILTON-LASKIBAR,%20I%C3%B1aki&ESEBERRI,%20Itziar&BEAUMONT,%20Pauline&COURTOIS,%20Arnaud&rft.genre=article


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