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Beneficial Effects of ϵ-Viniferin on Obesity and Related Health Alterations
| dc.rights.license | open | en_US |
| dc.contributor.author | GOMEZ-ZORITA, Saioa | |
| dc.contributor.author | MILTON-LASKIBAR, Iñaki | |
| dc.contributor.author | ESEBERRI, Itziar | |
| hal.structure.identifier | Unité de Recherche Œnologie [Villenave d'Ornon] [OENO] | |
| dc.contributor.author | BEAUMONT, Pauline | |
| hal.structure.identifier | Unité de Recherche Œnologie [Villenave d'Ornon] [OENO] | |
| dc.contributor.author | COURTOIS, Arnaud
IDREF: 092021301 | |
| hal.structure.identifier | Unité de Recherche Œnologie [Villenave d'Ornon] [OENO] | |
| dc.contributor.author | KRISA, Stéphanie | |
| dc.contributor.author | PORTILLO, María P | |
| dc.date.accessioned | 2024-04-11T13:49:22Z | |
| dc.date.available | 2024-04-11T13:49:22Z | |
| dc.date.issued | 2023-02-12 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/197568 | |
| dc.description.abstractEn | Viniferin is a phenolic compound belonging to the group of stilbenoids. In particular, ε-viniferin is a dimer of resveratrol, found in many plant genders, among which grapes (Vitis vinifera) are a primary source. Due to the fact that ε-viniferin is mainly present in the woody parts of plants, their use as a source of this bioactive compound is a very interesting issue in a circular economy. Both, in vitro studies carried out in pre-adipocytes and mature adipocytes and in vivo studies addressed in mice show that ε-viniferin is able to reduce fat accumulation. Moreover, it prevents the development of some obesity co-morbidities, such as type 2 diabetes, dyslipidemias, hypertension and fatty liver. ε-viniferin can be absorbed orally, but it shows a very low bioavailability. In this scenario, further research on animal models is needed to confirm the effects reported in a great number of studies; to determine which metabolites are involved, including the main one responsible for the biological effects observed and the mechanisms that justify these effects. In a further phase, human studies should be addressed in order to use ε-viniferin as a new tool for obesity management, as a nutraceutical or to be included in functional foods. © 2023 by the authors. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.subject.en | viniferin | |
| dc.subject.en | obesity | |
| dc.subject.en | glucose homeostasis | |
| dc.subject.en | dyslipidemia | |
| dc.subject.en | fatty liver | |
| dc.subject.en | hypertension | |
| dc.title.en | Beneficial Effects of ϵ-Viniferin on Obesity and Related Health Alterations | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.3390/nu15040928 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Biologie végétale | en_US |
| bordeaux.journal | Nutrients | en_US |
| bordeaux.page | 928 | en_US |
| bordeaux.volume | 15 | en_US |
| bordeaux.hal.laboratories | Oenologie - UMR 1366 | en_US |
| bordeaux.issue | 4 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | Bordeaux INP | en_US |
| bordeaux.institution | INRAE | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | false | |
| dc.rights.cc | CC BY | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nutrients&rft.date=2023-02-12&rft.volume=15&rft.issue=4&rft.spage=928&rft.epage=928&rft.au=GOMEZ-ZORITA,%20Saioa&MILTON-LASKIBAR,%20I%C3%B1aki&ESEBERRI,%20Itziar&BEAUMONT,%20Pauline&COURTOIS,%20Arnaud&rft.genre=article |
