Virtual mitochondrion: towards an integrated model of oxidative phosphorylation complexes and beyond.
Langue
en
Article de revue
Ce document a été publié dans
Biochemical Society Transactions. 2010-10, vol. 38, n° 5, p. 1215-9
Portland Press
Résumé en anglais
The modelling of OXPHOS (oxidative phosphorylation) in order to integrate all kinetic and thermodynamic aspects of chemiosmotic theory has a long history. We briefly review this history and show how new ways of modelling ...Lire la suite >
The modelling of OXPHOS (oxidative phosphorylation) in order to integrate all kinetic and thermodynamic aspects of chemiosmotic theory has a long history. We briefly review this history and show how new ways of modelling are required to integrate a local model of the individual respiratory complexes into a global model of OXPHOS and, beyond that, into a reliable overall model of central metabolism.< Réduire
Mots clés en anglais
oxidative phosphorylation
respiratory complex
stochastic and dynamical system modelling
Project ANR
Modélisation du métabolisme énergétique de la mitochondrie - ANR-07-BSYS-0005
Origine
Importé de halUnités de recherche