Virtual mitochondrion: towards an integrated model of oxidative phosphorylation complexes and beyond.
Language
en
Article de revue
This item was published in
Biochemical Society Transactions. 2010-10, vol. 38, n° 5, p. 1215-9
Portland Press
English Abstract
The modelling of OXPHOS (oxidative phosphorylation) in order to integrate all kinetic and thermodynamic aspects of chemiosmotic theory has a long history. We briefly review this history and show how new ways of modelling ...Read more >
The modelling of OXPHOS (oxidative phosphorylation) in order to integrate all kinetic and thermodynamic aspects of chemiosmotic theory has a long history. We briefly review this history and show how new ways of modelling are required to integrate a local model of the individual respiratory complexes into a global model of OXPHOS and, beyond that, into a reliable overall model of central metabolism.Read less <
English Keywords
oxidative phosphorylation
respiratory complex
stochastic and dynamical system modelling
ANR Project
Modélisation du métabolisme énergétique de la mitochondrie - ANR-07-BSYS-0005
Origin
Hal imported