COLOMBEL, Nina; FERREIRA, Guillaume; SULLIVAN, Regina M.; COUREAUD, Gérard

doi:10.1016/j.neubiorev.2023.105249

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COLOMBEL, Nina
École normale supérieure de Lyon [ENS de Lyon]

FERREIRA, Guillaume
Nutrition et Neurobiologie intégrée [NutriNeuro]

SULLIVAN, Regina M.

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Article de revue

Ce document a été publié dans

Neuroscience and Biobehavioral Reviews. 2023-08-01, vol. 151, p. 105249

Résumé en anglais

Infant survival relies on rapid identification, remembering and behavioral responsiveness to caregivers’ sensory cues. While neural circuits supporting infant attachment learning have largely remained elusive in children, use of invasive techniques has uncovered some of its features in rodents. During a 10-day sensitive period from birth, newborn rodents associate maternal odors with maternal pleasant or noxious thermo-tactile stimulation, which gives rise to a preference and approach behavior towards these odors, and blockade of avoidance learning. Here we review the neural circuitry supporting this neonatal odor learning, unique compared to adults, focusing specifically on the early roles of neurotransmitters such as glutamate, GABA (Gamma-AminoButyric Acid), serotonin, dopamine and norepinephrine, in the olfactory bulb, the anterior piriform cortex and amygdala. The review highlights the importance of deepening our knowledge of age-specific infant brain neurotransmitters and behavioral functioning that can be translated to improve the well-being of children during typical development and aid in treatment during atypical development in childhood clinical practice, and the care during rearing of domestic animals.< Réduire

URI

https://oskar-bordeaux.fr/handle/20.500.12278/183861

DOI

http://dx.doi.org/10.1016/j.neubiorev.2023.105249

Project ANR

Olfaction, cognition et comportement alimentaire chez le lapin nouveau-né - ANR-20-CE20-0019

Unités de recherche

NutriNeuro (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286