RECORDON-PINSON, Patricia; BLONDOT, Marie-Lise; BELLECAVE, Pantxika; LAFON, Marie-Edith; TUMIOTTO, Camille; MÉTIFIOT, Mathieu; ANDREOLA, Marie-Line

doi:10.3390/covid1010028

RECORDON-PINSON, Patricia
Microbiologie Fondamentale et Pathogénicité [MFP]

BLONDOT, Marie-Lise

BELLECAVE, Pantxika

Langue

Article de revue

Ce document a été publié dans

COVID. 2021-09, vol. 1, n° 1, p. 337-344

Résumé en anglais

Since the beginning of the pandemic, a race has been underway to detect SARS-CoV-2 virus infection (PCR screening, serological diagnostic kits), treat patients (drug repurposing, standard care) and develop a vaccine. After almost a year of active circulation worldwide, SARS-CoV-2 variants have appeared in different countries. Those variants include mutations in multiple regions of the genome, particularly in the spike gene. Because this surface protein is a key player in both the spread of the virus and the efficacy of vaccine strategies, the challenge is to efficiently monitor the appearance of spike mutations in the population. The present work describes a procedure based on the widely available Sanger technology to produce a full-length sequence of the spike gene from patient-derived samples.< Réduire

URI

https://oskar-bordeaux.fr/handle/20.500.12278/182226

DOI

http://dx.doi.org/10.3390/covid1010028

Unités de recherche

MFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234

Voir/Ouvrir

Métadonnées

Partager cette publication !

Licence d’utilisation du document

A Simple and Fast Method to Sequence the Full-Length Spike Gene for SARS-CoV-2 Variant Identification from Patient Samples

Langue

Ce document a été publié dans

Résumé en anglais

URI

DOI

Unités de recherche